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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBP
All Species:
50
Human Site:
Y237
Identified Species:
68.75
UniProt:
P20226
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20226
NP_003185.1
339
37698
Y237
S
R
L
A
A
R
K
Y
A
R
V
V
Q
K
L
Chimpanzee
Pan troglodytes
A6H907
376
41488
Y274
S
R
L
A
A
R
K
Y
A
R
V
V
Q
K
L
Rhesus Macaque
Macaca mulatta
XP_001085250
288
31595
F195
R
V
V
Q
K
L
G
F
P
A
K
F
L
D
F
Dog
Lupus familis
XP_854525
324
35731
Y222
S
R
L
A
A
R
K
Y
A
R
V
V
Q
K
L
Cat
Felis silvestris
Mouse
Mus musculus
P29037
316
34691
Y214
S
R
L
A
A
R
K
Y
A
R
V
V
Q
K
L
Rat
Rattus norvegicus
A6H909
344
38336
Y243
S
R
L
A
A
R
K
Y
A
R
V
V
Q
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O13270
302
33116
Y200
S
R
L
A
A
R
K
Y
A
R
V
V
Q
K
L
Frog
Xenopus laevis
P27633
297
32684
Y195
S
R
L
A
A
R
K
Y
A
R
V
V
Q
K
L
Zebra Danio
Brachydanio rerio
Q7SXL3
302
33001
Y200
S
R
L
A
A
R
K
Y
A
R
V
V
Q
K
L
Tiger Blowfish
Takifugu rubipres
Q6SJ94
322
35702
Y221
S
R
L
A
A
R
K
Y
A
R
V
V
Q
K
L
Fruit Fly
Dros. melanogaster
P20227
353
38433
Y251
S
R
L
A
A
R
K
Y
A
R
I
I
Q
K
L
Honey Bee
Apis mellifera
XP_623088
319
35720
Y218
S
R
L
A
A
R
K
Y
A
R
I
I
Q
K
L
Nematode Worm
Caenorhab. elegans
P32085
340
36629
Y240
S
R
L
A
A
R
K
Y
A
R
I
V
Q
K
L
Sea Urchin
Strong. purpuratus
P91809
265
29089
A173
V
V
Q
K
L
G
F
A
A
K
F
L
D
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P50159
200
22277
A108
I
Q
K
L
G
F
P
A
K
F
K
D
F
K
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28148
200
22378
A108
V
Q
K
L
G
F
P
A
K
F
K
D
F
K
I
Baker's Yeast
Sacchar. cerevisiae
P13393
240
26985
F148
R
I
I
Q
K
I
G
F
A
A
K
F
T
D
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.1
84.6
93.5
N.A.
91.1
50.2
N.A.
N.A.
87.9
81.4
80.8
58.7
58
61.6
52
59.5
Protein Similarity:
100
64
84.9
93.8
N.A.
91.4
63.6
N.A.
N.A.
88.5
84.6
84
67.5
67.4
66.9
60.8
65.4
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
100
100
100
100
86.6
86.6
93.3
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
100
100
100
100
100
100
100
20
Percent
Protein Identity:
N.A.
48.3
N.A.
47.7
48.6
N.A.
Protein Similarity:
N.A.
53.6
N.A.
52.5
57.5
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
20
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
71
71
0
0
18
83
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
12
6
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
12
6
12
0
12
6
12
12
6
12
% F
% Gly:
0
0
0
0
12
6
12
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
6
6
0
0
6
0
0
0
0
18
12
0
0
12
% I
% Lys:
0
0
12
6
12
0
71
0
12
6
24
0
0
83
6
% K
% Leu:
0
0
71
12
6
6
0
0
0
0
0
6
6
0
71
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
6
0
0
0
0
0
0
% P
% Gln:
0
12
6
12
0
0
0
0
0
0
0
0
71
0
0
% Q
% Arg:
12
71
0
0
0
71
0
0
0
71
0
0
0
0
0
% R
% Ser:
71
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% T
% Val:
12
12
6
0
0
0
0
0
0
0
53
59
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
71
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _