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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBP
All Species:
48.48
Human Site:
Y329
Identified Species:
66.67
UniProt:
P20226
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20226
NP_003185.1
339
37698
Y329
Y
E
A
F
E
N
I
Y
P
I
L
K
G
F
R
Chimpanzee
Pan troglodytes
A6H907
376
41488
Y366
Y
E
A
F
E
N
I
Y
P
I
L
K
G
F
R
Rhesus Macaque
Macaca mulatta
XP_001085250
288
31595
Y278
Y
E
A
F
E
N
I
Y
P
I
L
K
G
F
R
Dog
Lupus familis
XP_854525
324
35731
Y314
Y
E
A
F
E
N
I
Y
P
I
L
K
G
F
R
Cat
Felis silvestris
Mouse
Mus musculus
P29037
316
34691
Y306
Y
E
A
F
E
N
I
Y
P
I
L
K
G
F
R
Rat
Rattus norvegicus
A6H909
344
38336
Y335
Y
E
A
F
E
N
M
Y
P
I
L
E
S
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O13270
302
33116
Y292
Y
E
A
F
E
N
I
Y
P
I
L
K
G
F
R
Frog
Xenopus laevis
P27633
297
32684
Y287
Y
E
A
F
E
N
I
Y
P
I
L
K
G
F
R
Zebra Danio
Brachydanio rerio
Q7SXL3
302
33001
Y292
Y
E
A
F
E
N
I
Y
P
I
L
K
G
F
R
Tiger Blowfish
Takifugu rubipres
Q6SJ94
322
35702
Y313
Y
E
A
F
E
N
I
Y
P
I
L
R
G
F
R
Fruit Fly
Dros. melanogaster
P20227
353
38433
F343
Y
D
A
F
D
K
I
F
P
I
L
K
K
F
K
Honey Bee
Apis mellifera
XP_623088
319
35720
Y310
Y
E
A
F
D
N
I
Y
P
I
L
K
S
F
K
Nematode Worm
Caenorhab. elegans
P32085
340
36629
F328
K
R
D
I
D
E
A
F
G
Q
I
Y
P
I
L
Sea Urchin
Strong. purpuratus
P91809
265
29089
P256
D
A
F
N
N
I
Y
P
I
L
K
S
F
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P50159
200
22277
V191
A
F
E
N
I
Y
P
V
L
S
E
F
R
K
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28148
200
22378
V191
A
F
E
N
I
Y
P
V
L
R
E
F
R
K
V
Baker's Yeast
Sacchar. cerevisiae
P13393
240
26985
Y231
Y
Q
A
F
E
A
I
Y
P
V
L
S
E
F
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.1
84.6
93.5
N.A.
91.1
50.2
N.A.
N.A.
87.9
81.4
80.8
58.7
58
61.6
52
59.5
Protein Similarity:
100
64
84.9
93.8
N.A.
91.4
63.6
N.A.
N.A.
88.5
84.6
84
67.5
67.4
66.9
60.8
65.4
P-Site Identity:
100
100
100
100
N.A.
100
73.3
N.A.
N.A.
100
100
100
93.3
60
80
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
100
100
100
100
86.6
93.3
20
13.3
Percent
Protein Identity:
N.A.
48.3
N.A.
47.7
48.6
N.A.
Protein Similarity:
N.A.
53.6
N.A.
52.5
57.5
N.A.
P-Site Identity:
N.A.
0
N.A.
0
66.6
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
6
77
0
0
6
6
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
6
6
0
18
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
65
12
0
65
6
0
0
0
0
12
6
6
0
0
% E
% Phe:
0
12
6
77
0
0
0
12
0
0
0
12
6
77
0
% F
% Gly:
0
0
0
0
0
0
0
0
6
0
0
0
53
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
6
12
6
71
0
6
71
6
0
0
6
6
% I
% Lys:
6
0
0
0
0
6
0
0
0
0
6
59
6
18
24
% K
% Leu:
0
0
0
0
0
0
0
0
12
6
77
0
0
0
6
% L
% Met:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
18
6
65
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
6
77
0
0
0
6
0
0
% P
% Gln:
0
6
0
0
0
0
0
0
0
6
0
0
0
0
0
% Q
% Arg:
0
6
0
0
0
0
0
0
0
6
0
6
12
0
59
% R
% Ser:
0
0
0
0
0
0
0
0
0
6
0
12
12
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
0
6
0
0
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
77
0
0
0
0
12
6
71
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _