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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNA2 All Species: 26.36
Human Site: T184 Identified Species: 52.73
UniProt: P20248 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20248 NP_001228.1 432 48537 T184 D Y H E D I H T Y L R E M E V
Chimpanzee Pan troglodytes XP_517420 432 48476 T184 D Y H E D I H T Y L R E M E V
Rhesus Macaque Macaca mulatta XP_001100860 432 48504 T184 D Y H E D I H T Y L R E M E V
Dog Lupus familis XP_540965 432 48633 T184 D Y H E D I H T Y L R E M E V
Cat Felis silvestris
Mouse Mus musculus P51943 422 47265 T174 D Y Q E D I H T Y L R E M E V
Rat Rattus norvegicus Q6AY13 421 47676 R173 E Y A E E I H R Y L R E A E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513040 465 52108 T215 D Y H E D I H T Y L R E M E V
Chicken Gallus gallus P43449 395 44062 L150 V S D I H T Y L R E M E V K C
Frog Xenopus laevis P47827 415 46651 E170 E I H T Y L R E M E V K C K P
Zebra Danio Brachydanio rerio NP_694481 428 47894 T180 D Y A A E I H T H L R E M E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P14785 491 56134 E209 Q Y Q M D I L E Y F R E S E K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38819 450 50623 N195 Y A P E I H Y N L R V S E L K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99 91.4 N.A. 85.4 46.5 N.A. 69.2 63.4 57.6 58.7 N.A. 32.5 N.A. N.A. N.A.
Protein Similarity: 100 99.5 99.3 95.3 N.A. 90.9 60.1 N.A. 76.9 72.2 70.3 69.9 N.A. 48.8 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 66.6 N.A. 100 6.6 6.6 73.3 N.A. 46.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 80 N.A. 100 26.6 33.3 86.6 N.A. 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 17 9 0 0 0 0 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % C
% Asp: 59 0 9 0 59 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 17 0 0 67 17 0 0 17 0 17 0 84 9 75 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 50 0 9 9 67 0 9 0 0 0 0 0 0 % H
% Ile: 0 9 0 9 9 75 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 9 0 17 17 % K
% Leu: 0 0 0 0 0 9 9 9 9 67 0 0 0 9 0 % L
% Met: 0 0 0 9 0 0 0 0 9 0 9 0 59 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % P
% Gln: 9 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 9 9 9 75 0 0 0 0 % R
% Ser: 0 9 0 0 0 0 0 0 0 0 0 9 9 0 0 % S
% Thr: 0 0 0 9 0 9 0 59 0 0 0 0 0 0 0 % T
% Val: 9 0 0 0 0 0 0 0 0 0 17 0 9 0 67 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 75 0 0 9 0 17 0 67 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _