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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD22
All Species:
16.97
Human Site:
S743
Identified Species:
46.67
UniProt:
P20273
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20273
NP_001762.2
847
95348
S743
K
V
R
R
A
P
L
S
E
G
P
H
S
L
G
Chimpanzee
Pan troglodytes
Q9N1E6
332
37710
T233
G
K
F
L
S
N
D
T
V
Q
L
N
V
K
H
Rhesus Macaque
Macaca mulatta
XP_001111493
848
95478
S744
K
V
R
R
T
P
L
S
E
G
P
H
S
L
G
Dog
Lupus familis
XP_533695
853
96035
S747
K
I
R
R
V
P
V
S
E
D
P
H
S
L
G
Cat
Felis silvestris
Mouse
Mus musculus
P35329
862
96564
S758
K
A
R
R
T
P
L
S
E
G
P
Q
S
Q
G
Rat
Rattus norvegicus
NP_001100973
852
95445
T748
K
A
R
R
T
R
L
T
E
G
P
Q
S
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q0WYX8
949
106007
R806
F
I
E
A
S
R
P
R
V
T
G
D
K
A
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001091715
1043
117185
N941
T
L
D
F
K
G
Q
N
E
P
R
K
I
M
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796903
1010
110769
Y852
E
R
P
E
S
P
A
Y
S
D
S
N
T
D
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
86.5
64.4
N.A.
60
59
N.A.
N.A.
20
N.A.
24.7
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
100
38.4
91.7
76.7
N.A.
73.4
74
N.A.
N.A.
37.9
N.A.
42.5
N.A.
N.A.
N.A.
N.A.
36
P-Site Identity:
100
0
93.3
73.3
N.A.
73.3
60
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
93.3
86.6
N.A.
73.3
66.6
N.A.
N.A.
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
0
12
12
0
12
0
0
0
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
12
0
0
23
0
12
0
12
0
% D
% Glu:
12
0
12
12
0
0
0
0
67
0
0
0
0
0
0
% E
% Phe:
12
0
12
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
12
0
0
0
45
12
0
0
0
56
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
12
% H
% Ile:
0
23
0
0
0
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
56
12
0
0
12
0
0
0
0
0
0
12
12
12
0
% K
% Leu:
0
12
0
12
0
0
45
0
0
0
12
0
0
34
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
0
0
0
12
0
12
0
0
0
23
0
0
12
% N
% Pro:
0
0
12
0
0
56
12
0
0
12
56
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
12
0
0
12
0
23
0
23
0
% Q
% Arg:
0
12
56
56
0
23
0
12
0
0
12
0
0
0
12
% R
% Ser:
0
0
0
0
34
0
0
45
12
0
12
0
56
0
0
% S
% Thr:
12
0
0
0
34
0
0
23
0
12
0
0
12
0
0
% T
% Val:
0
23
0
0
12
0
12
0
23
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _