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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALOX5AP
All Species:
17.88
Human Site:
Y146
Identified Species:
43.7
UniProt:
P20292
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20292
NP_001620.2
161
18157
Y146
F
G
S
D
F
E
N
Y
I
K
T
I
S
T
T
Chimpanzee
Pan troglodytes
XP_001153488
150
16532
R136
H
F
L
P
A
A
P
R
A
A
L
L
G
R
L
Rhesus Macaque
Macaca mulatta
P30354
153
17257
F139
N
Y
Y
L
I
F
F
F
G
S
D
F
E
N
Y
Dog
Lupus familis
XP_534516
255
28152
Y240
F
G
S
D
F
E
N
Y
I
K
T
V
S
T
T
Cat
Felis silvestris
Mouse
Mus musculus
P30355
161
18118
Y146
F
G
S
D
F
E
N
Y
I
R
T
V
S
T
T
Rat
Rattus norvegicus
P20291
161
18052
Y146
F
G
S
D
F
E
N
Y
I
R
T
I
T
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508819
161
18120
Y146
F
G
S
D
F
E
M
Y
I
K
T
V
T
T
T
Chicken
Gallus gallus
XP_001233119
161
17887
H146
F
G
S
D
F
E
I
H
I
K
T
I
T
S
A
Frog
Xenopus laevis
NP_001088328
140
15585
I126
I
G
L
S
T
A
G
I
L
H
E
L
L
S
H
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788981
153
17069
A139
H
F
A
L
V
T
Y
A
G
V
D
V
K
R
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.2
93.1
61.1
N.A.
91.9
91.9
N.A.
90
82.6
30.4
N.A.
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
44.7
94.4
62.7
N.A.
95.6
96.2
N.A.
95.6
90
46.5
N.A.
N.A.
N.A.
N.A.
N.A.
47.8
P-Site Identity:
100
0
0
93.3
N.A.
86.6
86.6
N.A.
80
66.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
6.6
6.6
100
N.A.
100
100
N.A.
93.3
86.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
20
0
10
10
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
60
0
0
0
0
0
0
20
0
0
0
0
% D
% Glu:
0
0
0
0
0
60
0
0
0
0
10
0
10
0
0
% E
% Phe:
60
20
0
0
60
10
10
10
0
0
0
10
0
0
0
% F
% Gly:
0
70
0
0
0
0
10
0
20
0
0
0
10
0
0
% G
% His:
20
0
0
0
0
0
0
10
0
10
0
0
0
0
10
% H
% Ile:
10
0
0
0
10
0
10
10
60
0
0
30
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
40
0
0
10
0
0
% K
% Leu:
0
0
20
20
0
0
0
0
10
0
10
20
10
0
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% M
% Asn:
10
0
0
0
0
0
40
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
20
0
0
0
20
0
% R
% Ser:
0
0
60
10
0
0
0
0
0
10
0
0
30
20
0
% S
% Thr:
0
0
0
0
10
10
0
0
0
0
60
0
30
50
50
% T
% Val:
0
0
0
0
10
0
0
0
0
10
0
40
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
0
10
50
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _