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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNFRSF1B
All Species:
13.33
Human Site:
S327
Identified Species:
36.67
UniProt:
P20333
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20333
NP_001057.1
461
48291
S327
L
I
T
A
P
S
S
S
S
S
S
L
E
S
S
Chimpanzee
Pan troglodytes
XP_514405
652
68964
S518
L
I
T
A
P
S
S
S
S
S
S
L
E
S
S
Rhesus Macaque
Macaca mulatta
XP_001105753
462
48065
S328
T
T
V
P
S
S
S
S
S
S
L
E
S
S
A
Dog
Lupus familis
XP_544562
450
46595
S316
A
P
S
S
S
S
S
S
L
E
S
A
A
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P25119
474
50301
S329
T
T
A
P
S
S
S
S
S
S
L
E
S
S
A
Rat
Rattus norvegicus
Q80WY6
474
50130
S329
T
T
A
P
S
S
S
S
S
S
L
E
S
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989770
462
50097
A322
G
S
S
L
D
N
A
A
G
S
E
R
L
S
V
Frog
Xenopus laevis
NP_001086287
387
44550
E256
K
D
H
N
R
E
S
E
S
G
K
H
L
F
Q
Zebra Danio
Brachydanio rerio
XP_001336498
413
44750
V281
P
I
T
D
V
N
T
V
E
Q
D
P
S
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.8
95.4
69.4
N.A.
60.3
59.4
N.A.
N.A.
35.2
22.1
27.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
69.6
96
78
N.A.
71.7
70.4
N.A.
N.A.
46.9
37
43.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
40
40
N.A.
40
40
N.A.
N.A.
13.3
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
46.6
53.3
N.A.
46.6
46.6
N.A.
N.A.
40
13.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
23
23
0
0
12
12
0
0
0
12
12
0
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
12
12
0
0
0
0
0
12
0
0
0
0
% D
% Glu:
0
0
0
0
0
12
0
12
12
12
12
34
23
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
12
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% K
% Leu:
23
0
0
12
0
0
0
0
12
0
34
23
23
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
23
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
12
0
34
23
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
12
0
0
0
12
12
% Q
% Arg:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% R
% Ser:
0
12
23
12
45
67
78
67
67
67
34
0
45
78
45
% S
% Thr:
34
34
34
0
0
0
12
0
0
0
0
0
0
0
0
% T
% Val:
0
0
12
0
12
0
0
12
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _