KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB4A
All Species:
47.58
Human Site:
Y77
Identified Species:
74.76
UniProt:
P20338
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20338
NP_004569.2
213
23871
Y77
F
R
S
V
T
R
S
Y
Y
R
G
A
A
G
A
Chimpanzee
Pan troglodytes
XP_001145983
561
60056
Y77
F
R
S
V
T
R
S
Y
Y
R
G
A
A
G
A
Rhesus Macaque
Macaca mulatta
XP_001092499
200
21803
R80
L
V
Y
D
I
T
S
R
E
T
Y
N
S
L
A
Dog
Lupus familis
XP_536353
218
24344
Y82
F
R
S
V
T
R
S
Y
Y
R
G
A
A
G
A
Cat
Felis silvestris
Mouse
Mus musculus
P56371
213
23920
Y77
F
R
S
V
T
R
S
Y
Y
R
G
A
A
G
A
Rat
Rattus norvegicus
P05714
213
23888
Y77
F
R
S
V
T
R
S
Y
Y
R
G
A
A
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90965
212
23503
R77
S
I
T
R
S
Y
Y
R
G
A
A
G
A
L
L
Frog
Xenopus laevis
NP_001080671
213
23840
Y77
F
R
S
V
T
R
S
Y
Y
R
G
A
A
G
A
Zebra Danio
Brachydanio rerio
Q6PHI9
213
23984
Y77
F
R
S
V
T
R
S
Y
Y
R
G
A
A
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523777
213
23555
Y77
F
R
S
V
T
R
S
Y
Y
R
G
A
A
G
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791693
210
23410
Y77
F
R
S
V
T
R
S
Y
Y
R
G
A
A
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49103
209
22983
R77
S
I
T
R
S
Y
Y
R
G
A
A
G
A
L
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28188
203
22630
Y77
F
R
T
I
T
S
S
Y
Y
R
G
A
H
G
I
Baker's Yeast
Sacchar. cerevisiae
P38555
223
24451
Y82
Y
R
A
I
T
S
A
Y
Y
R
G
A
V
G
A
Red Bread Mold
Neurospora crassa
P33723
203
22458
Y77
F
R
T
I
T
S
S
Y
Y
R
G
A
H
G
I
Conservation
Percent
Protein Identity:
100
31.1
76.5
97.2
N.A.
97.6
98.5
N.A.
N.A.
52.5
85.4
96.2
N.A.
76.5
N.A.
N.A.
85.4
Protein Similarity:
100
34.4
82.1
97.7
N.A.
99.5
99.5
N.A.
N.A.
69
90.6
98.1
N.A.
87.7
N.A.
N.A.
91
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
6.6
100
100
N.A.
100
N.A.
N.A.
100
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
N.A.
20
100
100
N.A.
100
N.A.
N.A.
100
Percent
Protein Identity:
N.A.
51.6
N.A.
40.8
43
39.4
Protein Similarity:
N.A.
67.6
N.A.
59.1
60.5
58.2
P-Site Identity:
N.A.
6.6
N.A.
66.6
60
66.6
P-Site Similarity:
N.A.
20
N.A.
80
86.6
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
7
0
0
14
14
80
74
0
74
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% E
% Phe:
74
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
14
0
80
14
0
80
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% H
% Ile:
0
14
0
20
7
0
0
0
0
0
0
0
0
0
14
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
7
0
0
0
0
0
0
0
0
0
0
0
0
20
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
80
0
14
0
60
0
20
0
80
0
0
0
0
0
% R
% Ser:
14
0
60
0
14
20
80
0
0
0
0
0
7
0
0
% S
% Thr:
0
0
27
0
80
7
0
0
0
7
0
0
0
0
0
% T
% Val:
0
7
0
60
0
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
0
14
14
80
80
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _