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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAB5A All Species: 27.27
Human Site: S167 Identified Species: 46.15
UniProt: P20339 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20339 NP_004153.2 215 23659 S167 M E T S A K T S M N V N E I F
Chimpanzee Pan troglodytes XP_516319 216 23697 S167 M E T S A K T S M N V N E I F
Rhesus Macaque Macaca mulatta XP_001086669 215 23622 S167 M E T S A K T S M D V N E I F
Dog Lupus familis XP_856128 222 24457 A167 M E T S A K T A M N V N D L F
Cat Felis silvestris
Mouse Mus musculus Q9CQD1 215 23580 S167 M E T S A K T S M N V N E I F
Rat Rattus norvegicus Q6GQP4 194 21350 L158 N A I N I E E L F Q G I S R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508982 215 23635 S167 M E T S A K T S M N V N E I F
Chicken Gallus gallus Q98932 216 23535 A168 M E T S A K T A M N V N E I F
Frog Xenopus laevis NP_001080535 216 23558 S168 M E T S A K T S V N V N E I F
Zebra Danio Brachydanio rerio NP_958893 216 23476 S168 M E T S A K T S M N V N E I F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783878 216 23603 A166 M E T S A K T A M N V N D I F
Poplar Tree Populus trichocarpa
Maize Zea mays Q05737 203 22457 A167 Q A F M A M A A S I K D R M A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P31582 200 21635 F164 A T N V K D I F Y E I A K R L
Baker's Yeast Sacchar. cerevisiae P36017 210 23062 P172 L G I G E K I P L K T A E E Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 94.4 79.2 N.A. 98.1 45.1 N.A. 97.2 87 91.6 92.5 N.A. N.A. N.A. N.A. 81.4
Protein Similarity: 100 99.5 98.5 88.2 N.A. 99 62.7 N.A. 99 91.6 95.3 94.9 N.A. N.A. N.A. N.A. 88.4
P-Site Identity: 100 100 93.3 80 N.A. 100 0 N.A. 100 93.3 93.3 100 N.A. N.A. N.A. N.A. 86.6
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 100 100 100 100 N.A. N.A. N.A. N.A. 100
Percent
Protein Identity: N.A. 40.4 N.A. 59 54.4 N.A.
Protein Similarity: N.A. 57.2 N.A. 70.7 68.3 N.A.
P-Site Identity: N.A. 6.6 N.A. 0 13.3 N.A.
P-Site Similarity: N.A. 26.6 N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 15 0 0 79 0 8 29 0 0 0 15 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 8 0 8 15 0 0 % D
% Glu: 0 72 0 0 8 8 8 0 0 8 0 0 65 8 0 % E
% Phe: 0 0 8 0 0 0 0 8 8 0 0 0 0 0 72 % F
% Gly: 0 8 0 8 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 15 0 8 0 15 0 0 8 8 8 0 65 0 % I
% Lys: 0 0 0 0 8 79 0 0 0 8 8 0 8 0 0 % K
% Leu: 8 0 0 0 0 0 0 8 8 0 0 0 0 8 8 % L
% Met: 72 0 0 8 0 8 0 0 65 0 0 0 0 8 0 % M
% Asn: 8 0 8 8 0 0 0 0 0 65 0 72 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 15 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 8 15 0 % R
% Ser: 0 0 0 72 0 0 0 50 8 0 0 0 8 0 0 % S
% Thr: 0 8 72 0 0 0 72 0 0 0 8 0 0 0 0 % T
% Val: 0 0 0 8 0 0 0 0 8 0 72 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _