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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB5A
All Species:
20
Human Site:
T205
Identified Species:
33.85
UniProt:
P20339
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20339
NP_004153.2
215
23659
T205
G
V
D
L
T
E
P
T
Q
P
T
R
N
Q
C
Chimpanzee
Pan troglodytes
XP_516319
216
23697
T206
G
V
D
L
T
E
P
T
Q
P
T
R
N
Q
C
Rhesus Macaque
Macaca mulatta
XP_001086669
215
23622
T205
G
V
D
L
T
E
P
T
R
P
T
R
S
Q
C
Dog
Lupus familis
XP_856128
222
24457
S212
G
V
D
L
H
E
Q
S
Q
Q
N
K
S
Q
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQD1
215
23580
A205
G
V
D
L
T
E
P
A
Q
P
A
R
S
Q
C
Rat
Rattus norvegicus
Q6GQP4
194
21350
Q185
G
G
I
K
L
G
N
Q
S
L
Q
A
G
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508982
215
23635
T205
G
V
D
L
T
E
H
T
L
P
S
R
S
Q
C
Chicken
Gallus gallus
Q98932
216
23535
S206
V
V
D
L
Q
E
S
S
Q
P
S
R
S
Q
C
Frog
Xenopus laevis
NP_001080535
216
23558
A206
G
V
D
L
T
E
T
A
Q
P
T
K
S
Q
C
Zebra Danio
Brachydanio rerio
NP_958893
216
23476
A206
G
V
D
L
T
E
T
A
Q
P
T
K
A
P
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783878
216
23603
N206
G
V
D
L
T
E
S
N
Q
Q
S
S
G
G
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q05737
203
22457
V194
V
Q
I
R
G
Q
P
V
N
Q
K
T
S
C
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P31582
200
21635
A191
V
L
P
N
G
P
G
A
T
A
V
S
S
S
C
Baker's Yeast
Sacchar. cerevisiae
P36017
210
23062
D200
V
D
L
N
A
A
N
D
G
T
S
A
N
S
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
94.4
79.2
N.A.
98.1
45.1
N.A.
97.2
87
91.6
92.5
N.A.
N.A.
N.A.
N.A.
81.4
Protein Similarity:
100
99.5
98.5
88.2
N.A.
99
62.7
N.A.
99
91.6
95.3
94.9
N.A.
N.A.
N.A.
N.A.
88.4
P-Site Identity:
100
100
86.6
53.3
N.A.
80
6.6
N.A.
73.3
60
73.3
66.6
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
73.3
N.A.
86.6
13.3
N.A.
86.6
80
86.6
73.3
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
40.4
N.A.
59
54.4
N.A.
Protein Similarity:
N.A.
57.2
N.A.
70.7
68.3
N.A.
P-Site Identity:
N.A.
13.3
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
29
0
8
8
15
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
86
% C
% Asp:
0
8
72
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
72
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
72
8
0
0
15
8
8
0
8
0
0
0
15
8
0
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
8
22
0
0
0
% K
% Leu:
0
8
8
72
8
0
0
0
8
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
15
0
0
15
8
8
0
8
0
22
0
0
% N
% Pro:
0
0
8
0
0
8
36
0
0
58
0
0
0
8
0
% P
% Gln:
0
8
0
0
8
8
8
8
58
22
8
0
0
58
0
% Q
% Arg:
0
0
0
8
0
0
0
0
8
0
0
43
0
8
8
% R
% Ser:
0
0
0
0
0
0
15
15
8
0
29
15
58
15
0
% S
% Thr:
0
0
0
0
58
0
15
29
8
8
36
8
0
0
0
% T
% Val:
29
72
0
0
0
0
0
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _