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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PMCH All Species: 13.33
Human Site: S25 Identified Species: 58.67
UniProt: P20382 Number Species: 5
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20382 NP_002665.2 165 18679 S25 F S Q G I L L S A S K S I R N
Chimpanzee Pan troglodytes NP_001128240 165 18664 S25 F S Q G I L L S A S K S I R N
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P56942 166 18627 S25 F S Q G I L L S A S K S I R N
Rat Rattus norvegicus P14200 165 18464 S25 F S H G I L L S A S K S I R N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508069 165 18527 R28 L S A T K S M R N E E D D G M
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001343119 201 22525 A52 N N L P K I M A S S Y I I I F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 N.A. N.A. N.A. 86.7 81.8 N.A. 75.7 N.A. N.A. 22.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.7 N.A. N.A. N.A. 94.5 92.1 N.A. 85.4 N.A. N.A. 44.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. N.A. N.A. 100 93.3 N.A. 6.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. N.A. N.A. 100 93.3 N.A. 20 N.A. N.A. 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 0 0 0 17 67 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 17 17 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 17 17 0 0 0 0 % E
% Phe: 67 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % F
% Gly: 0 0 0 67 0 0 0 0 0 0 0 0 0 17 0 % G
% His: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 67 17 0 0 0 0 0 17 84 17 0 % I
% Lys: 0 0 0 0 34 0 0 0 0 0 67 0 0 0 0 % K
% Leu: 17 0 17 0 0 67 67 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 17 % M
% Asn: 17 17 0 0 0 0 0 0 17 0 0 0 0 0 67 % N
% Pro: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 17 0 0 0 0 0 67 0 % R
% Ser: 0 84 0 0 0 17 0 67 17 84 0 67 0 0 0 % S
% Thr: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _