KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH3
All Species:
8.79
Human Site:
S420
Identified Species:
17.58
UniProt:
P20585
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20585
NP_002430.2
1137
127440
S420
E
L
E
T
R
M
S
S
L
Q
P
V
E
L
L
Chimpanzee
Pan troglodytes
XP_526872
653
74467
Rhesus Macaque
Macaca mulatta
XP_001110439
1124
126700
N408
E
L
E
T
R
M
S
N
L
Q
P
V
E
L
L
Dog
Lupus familis
XP_536307
1124
126796
C409
E
L
E
T
R
I
L
C
L
Q
P
V
E
M
L
Cat
Felis silvestris
Mouse
Mus musculus
P13705
1091
123056
S378
E
L
E
T
R
I
S
S
L
Q
P
V
E
L
L
Rat
Rattus norvegicus
XP_001065837
1105
124697
S378
E
L
E
T
R
T
A
S
L
Q
P
V
E
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512218
1058
119728
R369
Q
S
E
K
C
I
N
R
I
T
S
I
C
V
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103184
1083
121769
V379
R
I
L
R
I
Q
P
V
E
I
L
V
P
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193092
988
109454
H318
S
E
L
D
T
R
L
H
H
I
Q
P
V
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65607
1081
119348
K362
L
E
D
D
K
E
M
K
L
E
A
A
E
K
G
Baker's Yeast
Sacchar. cerevisiae
P25336
1018
116515
F347
P
L
H
V
A
K
F
F
K
D
I
S
C
P
L
Red Bread Mold
Neurospora crassa
Q7SD11
1145
125674
P385
T
R
L
L
H
I
S
P
C
E
F
L
I
V
G
Conservation
Percent
Protein Identity:
100
54.1
95.6
83.1
N.A.
78.3
78.8
N.A.
71.5
N.A.
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
56.1
96.6
88.7
N.A.
86
86.2
N.A.
81.2
N.A.
N.A.
68.5
N.A.
N.A.
N.A.
N.A.
57.4
P-Site Identity:
100
0
93.3
73.3
N.A.
93.3
86.6
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
0
100
86.6
N.A.
100
93.3
N.A.
46.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
30.4
36.7
Protein Similarity:
N.A.
N.A.
N.A.
55.8
49.5
55.9
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
9
0
0
0
9
9
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
9
9
0
0
0
17
0
0
% C
% Asp:
0
0
9
17
0
0
0
0
0
9
0
0
0
0
9
% D
% Glu:
42
17
50
0
0
9
0
0
9
17
0
0
50
9
0
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% G
% His:
0
0
9
0
9
0
0
9
9
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
34
0
0
9
17
9
9
9
0
0
% I
% Lys:
0
0
0
9
9
9
0
9
9
0
0
0
0
9
0
% K
% Leu:
9
50
25
9
0
0
17
0
50
0
9
9
0
34
59
% L
% Met:
0
0
0
0
0
17
9
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
9
9
0
0
42
9
9
9
0
% P
% Gln:
9
0
0
0
0
9
0
0
0
42
9
0
0
0
0
% Q
% Arg:
9
9
0
9
42
9
0
9
0
0
0
0
0
0
9
% R
% Ser:
9
9
0
0
0
0
34
25
0
0
9
9
0
9
0
% S
% Thr:
9
0
0
42
9
9
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
9
0
0
0
50
9
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _