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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
M6PR
All Species:
18.48
Human Site:
S158
Identified Species:
36.97
UniProt:
P20645
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20645
NP_002346.1
277
30993
S158
A
D
N
F
N
P
V
S
E
E
R
G
K
V
Q
Chimpanzee
Pan troglodytes
XP_001137994
244
27171
T149
M
I
S
C
N
R
H
T
L
A
D
N
F
N
P
Rhesus Macaque
Macaca mulatta
XP_001113975
278
31085
S159
A
D
N
F
N
P
V
S
E
E
R
G
K
V
Q
Dog
Lupus familis
XP_534894
396
43228
S277
A
D
N
F
N
P
V
S
E
E
R
G
K
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
P24668
278
31154
S159
A
A
N
F
N
P
V
S
E
E
R
G
K
V
Q
Rat
Rattus norvegicus
Q6AY20
278
31077
S159
A
G
N
F
N
P
V
S
E
E
R
G
K
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514710
258
28364
I162
F
N
G
S
D
W
I
I
L
S
Y
K
G
G
D
Chicken
Gallus gallus
XP_416477
298
33190
I172
G
S
D
W
I
M
L
I
Y
K
G
G
D
S
Y
Frog
Xenopus laevis
NP_001080870
273
29899
C175
E
M
D
S
S
L
A
C
P
P
E
E
S
H
L
Zebra Danio
Brachydanio rerio
NP_998370
265
29164
V165
F
E
L
D
T
T
A
V
C
P
A
V
S
S
K
Tiger Blowfish
Takifugu rubipres
NP_001033033
272
30118
C174
R
L
D
S
S
A
V
C
P
A
L
Q
S
K
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784873
183
20114
A88
L
A
K
V
A
L
H
A
V
G
R
T
T
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
98.9
66.4
N.A.
91.7
91
N.A.
54.1
52
59.2
48.7
42.9
N.A.
N.A.
N.A.
30.3
Protein Similarity:
100
87.7
99.2
68.6
N.A.
95.6
95.6
N.A.
63.9
63.7
72.9
66.7
59.9
N.A.
N.A.
N.A.
42.6
P-Site Identity:
100
6.6
100
100
N.A.
93.3
86.6
N.A.
0
6.6
0
0
6.6
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
100
100
N.A.
93.3
93.3
N.A.
20
33.3
13.3
13.3
20
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
17
0
0
9
9
17
9
0
17
9
0
0
9
0
% A
% Cys:
0
0
0
9
0
0
0
17
9
0
0
0
0
0
0
% C
% Asp:
0
25
25
9
9
0
0
0
0
0
9
0
9
0
9
% D
% Glu:
9
9
0
0
0
0
0
0
42
42
9
9
0
0
0
% E
% Phe:
17
0
0
42
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
9
9
9
0
0
0
0
0
0
9
9
50
9
9
0
% G
% His:
0
0
0
0
0
0
17
0
0
0
0
0
0
9
0
% H
% Ile:
0
9
0
0
9
0
9
17
0
0
0
0
0
9
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
9
0
9
42
9
9
% K
% Leu:
9
9
9
0
0
17
9
0
17
0
9
0
0
0
17
% L
% Met:
9
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
42
0
50
0
0
0
0
0
0
9
0
9
0
% N
% Pro:
0
0
0
0
0
42
0
0
17
17
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
42
% Q
% Arg:
9
0
0
0
0
9
0
0
0
0
50
0
0
0
0
% R
% Ser:
0
9
9
25
17
0
0
42
0
9
0
0
25
17
0
% S
% Thr:
0
0
0
0
9
9
0
9
0
0
0
9
9
0
9
% T
% Val:
0
0
0
9
0
0
50
9
9
0
0
9
0
34
0
% V
% Trp:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _