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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
M6PR
All Species:
17.88
Human Site:
S24
Identified Species:
35.76
UniProt:
P20645
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20645
NP_002346.1
277
30993
S24
L
A
V
A
V
R
E
S
W
Q
T
E
E
K
T
Chimpanzee
Pan troglodytes
XP_001137994
244
27171
A18
G
L
L
L
L
L
L
A
V
A
V
R
E
S
W
Rhesus Macaque
Macaca mulatta
XP_001113975
278
31085
S25
L
A
V
A
V
R
E
S
W
Q
A
E
E
K
T
Dog
Lupus familis
XP_534894
396
43228
S143
L
A
V
A
V
R
E
S
W
Q
T
E
E
K
T
Cat
Felis silvestris
Mouse
Mus musculus
P24668
278
31154
S25
L
A
V
A
V
R
E
S
W
Q
I
E
E
K
S
Rat
Rattus norvegicus
Q6AY20
278
31077
S25
L
A
V
A
V
R
E
S
W
Q
I
E
E
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514710
258
28364
G27
A
P
V
A
P
R
Q
G
W
A
I
R
R
L
R
Chicken
Gallus gallus
XP_416477
298
33190
R24
L
G
S
A
P
A
R
R
L
R
P
V
P
E
Q
Frog
Xenopus laevis
NP_001080870
273
29899
D33
D
C
Q
L
V
G
G
D
K
K
S
A
T
E
Q
Zebra Danio
Brachydanio rerio
NP_998370
265
29164
S25
V
Q
A
R
F
N
T
S
N
C
K
L
V
S
D
Tiger Blowfish
Takifugu rubipres
NP_001033033
272
30118
C27
I
L
D
G
G
P
V
C
A
T
N
S
T
Q
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784873
183
20114
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
98.9
66.4
N.A.
91.7
91
N.A.
54.1
52
59.2
48.7
42.9
N.A.
N.A.
N.A.
30.3
Protein Similarity:
100
87.7
99.2
68.6
N.A.
95.6
95.6
N.A.
63.9
63.7
72.9
66.7
59.9
N.A.
N.A.
N.A.
42.6
P-Site Identity:
100
6.6
93.3
100
N.A.
86.6
86.6
N.A.
26.6
13.3
6.6
6.6
0
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
93.3
100
N.A.
93.3
93.3
N.A.
33.3
26.6
26.6
13.3
20
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
42
9
59
0
9
0
9
9
17
9
9
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
9
0
9
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
0
0
9
0
0
0
0
0
0
9
% D
% Glu:
0
0
0
0
0
0
42
0
0
0
0
42
50
17
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
9
9
9
9
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
9
9
0
0
42
0
% K
% Leu:
50
17
9
17
9
9
9
0
9
0
0
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
9
0
9
0
0
0
0
% N
% Pro:
0
9
0
0
17
9
0
0
0
0
9
0
9
0
0
% P
% Gln:
0
9
9
0
0
0
9
0
0
42
0
0
0
9
17
% Q
% Arg:
0
0
0
9
0
50
9
9
0
9
0
17
9
0
9
% R
% Ser:
0
0
9
0
0
0
0
50
0
0
9
9
0
17
25
% S
% Thr:
0
0
0
0
0
0
9
0
0
9
17
0
17
0
25
% T
% Val:
9
0
50
0
50
0
9
0
9
0
9
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _