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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
M6PR
All Species:
24.55
Human Site:
S246
Identified Species:
49.09
UniProt:
P20645
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20645
NP_002346.1
277
30993
S246
G
C
D
F
V
C
R
S
K
P
R
N
V
P
A
Chimpanzee
Pan troglodytes
XP_001137994
244
27171
G216
L
Y
Q
R
L
V
V
G
A
K
G
M
E
Q
F
Rhesus Macaque
Macaca mulatta
XP_001113975
278
31085
S247
G
C
D
F
V
C
R
S
K
P
R
N
V
P
A
Dog
Lupus familis
XP_534894
396
43228
S365
G
C
D
F
V
C
R
S
K
P
R
N
V
P
A
Cat
Felis silvestris
Mouse
Mus musculus
P24668
278
31154
S247
G
C
D
F
V
C
R
S
K
P
R
N
V
P
A
Rat
Rattus norvegicus
Q6AY20
278
31077
S247
G
C
D
F
V
C
R
S
K
P
R
S
V
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514710
258
28364
L229
C
P
P
E
D
T
H
L
S
V
G
S
V
L
L
Chicken
Gallus gallus
XP_416477
298
33190
F259
T
V
Y
I
V
G
G
F
L
Y
Q
R
L
I
V
Frog
Xenopus laevis
NP_001080870
273
29899
S242
G
C
D
F
V
C
R
S
R
P
R
T
S
E
T
Zebra Danio
Brachydanio rerio
NP_998370
265
29164
R234
C
D
F
V
C
R
S
R
G
N
R
E
E
P
P
Tiger Blowfish
Takifugu rubipres
NP_001033033
272
30118
S241
G
C
D
F
V
C
R
S
R
T
R
E
E
V
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784873
183
20114
Q155
V
C
R
C
N
K
K
Q
H
S
K
S
Y
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
98.9
66.4
N.A.
91.7
91
N.A.
54.1
52
59.2
48.7
42.9
N.A.
N.A.
N.A.
30.3
Protein Similarity:
100
87.7
99.2
68.6
N.A.
95.6
95.6
N.A.
63.9
63.7
72.9
66.7
59.9
N.A.
N.A.
N.A.
42.6
P-Site Identity:
100
0
100
100
N.A.
100
93.3
N.A.
6.6
6.6
66.6
13.3
60
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
13.3
20
73.3
13.3
66.6
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
42
% A
% Cys:
17
67
0
9
9
59
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
59
0
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
0
0
0
0
0
17
25
9
0
% E
% Phe:
0
0
9
59
0
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
59
0
0
0
0
9
9
9
9
0
17
0
0
0
9
% G
% His:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
9
9
0
42
9
9
0
0
9
0
% K
% Leu:
9
0
0
0
9
0
0
9
9
0
0
0
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
9
0
34
0
0
0
% N
% Pro:
0
9
9
0
0
0
0
0
0
50
0
0
0
50
17
% P
% Gln:
0
0
9
0
0
0
0
9
0
0
9
0
0
9
0
% Q
% Arg:
0
0
9
9
0
9
59
9
17
0
67
9
0
0
0
% R
% Ser:
0
0
0
0
0
0
9
59
9
9
0
25
9
0
0
% S
% Thr:
9
0
0
0
0
9
0
0
0
9
0
9
0
0
9
% T
% Val:
9
9
0
9
67
9
9
0
0
9
0
0
50
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
9
0
0
0
0
0
0
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _