KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
M6PR
All Species:
18.18
Human Site:
S267
Identified Species:
36.36
UniProt:
P20645
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20645
NP_002346.1
277
30993
S267
D
D
Q
L
G
E
E
S
E
E
R
D
D
H
L
Chimpanzee
Pan troglodytes
XP_001137994
244
27171
A237
Q
D
L
G
N
L
V
A
V
S
N
R
A
A
G
Rhesus Macaque
Macaca mulatta
XP_001113975
278
31085
S268
D
D
Q
L
G
E
E
S
E
E
R
D
D
H
L
Dog
Lupus familis
XP_534894
396
43228
S386
D
D
Q
L
G
E
E
S
E
E
R
D
D
H
L
Cat
Felis silvestris
Mouse
Mus musculus
P24668
278
31154
S268
D
D
Q
L
G
E
E
S
E
E
R
D
D
H
L
Rat
Rattus norvegicus
Q6AY20
278
31077
S268
D
D
Q
L
G
E
E
S
E
E
R
D
D
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514710
258
28364
A250
C
R
Q
G
G
P
R
A
G
P
Q
T
G
L
A
Chicken
Gallus gallus
XP_416477
298
33190
W280
Q
F
P
H
F
A
F
W
Q
D
L
G
N
L
V
Frog
Xenopus laevis
NP_001080870
273
29899
P263
D
D
Q
L
G
E
E
P
E
E
R
D
D
H
L
Zebra Danio
Brachydanio rerio
NP_998370
265
29164
P255
T
E
P
L
G
E
E
P
E
E
R
D
D
H
L
Tiger Blowfish
Takifugu rubipres
NP_001033033
272
30118
P262
S
E
P
S
E
D
D
P
E
E
R
D
D
H
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784873
183
20114
R176
G
L
D
E
E
E
E
R
D
E
N
I
L
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
98.9
66.4
N.A.
91.7
91
N.A.
54.1
52
59.2
48.7
42.9
N.A.
N.A.
N.A.
30.3
Protein Similarity:
100
87.7
99.2
68.6
N.A.
95.6
95.6
N.A.
63.9
63.7
72.9
66.7
59.9
N.A.
N.A.
N.A.
42.6
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
13.3
0
93.3
73.3
46.6
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
26.6
26.6
93.3
80
66.6
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
17
0
0
0
0
9
9
9
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
59
9
0
0
9
9
0
9
9
0
67
67
0
0
% D
% Glu:
0
17
0
9
17
67
67
0
67
75
0
0
0
0
0
% E
% Phe:
0
9
0
0
9
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
17
67
0
0
0
9
0
0
9
9
0
9
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
67
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
9
59
0
9
0
0
0
0
9
0
9
17
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
17
0
9
0
0
% N
% Pro:
0
0
25
0
0
9
0
25
0
9
0
0
0
9
0
% P
% Gln:
17
0
59
0
0
0
0
0
9
0
9
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
9
9
0
0
67
9
0
0
0
% R
% Ser:
9
0
0
9
0
0
0
42
0
9
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _