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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
M6PR
All Species:
19.7
Human Site:
Y73
Identified Species:
39.39
UniProt:
P20645
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20645
NP_002346.1
277
30993
Y73
Q
G
S
D
T
Y
I
Y
I
F
R
V
C
R
E
Chimpanzee
Pan troglodytes
XP_001137994
244
27171
G65
K
S
F
E
S
T
V
G
Q
G
S
D
T
Y
I
Rhesus Macaque
Macaca mulatta
XP_001113975
278
31085
Y74
Q
G
S
D
T
Y
I
Y
I
F
R
V
C
R
E
Dog
Lupus familis
XP_534894
396
43228
Y192
Q
G
P
D
T
Y
I
Y
M
F
R
V
C
R
E
Cat
Felis silvestris
Mouse
Mus musculus
P24668
278
31154
Y74
Q
G
S
D
T
Y
S
Y
I
F
R
V
C
R
E
Rat
Rattus norvegicus
Q6AY20
278
31077
Y74
Q
G
S
D
T
Y
S
Y
I
F
R
V
C
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514710
258
28364
L78
A
G
E
K
T
C
D
L
L
G
E
G
D
R
E
Chicken
Gallus gallus
XP_416477
298
33190
S80
A
E
P
L
S
E
K
S
C
D
V
V
G
D
E
Frog
Xenopus laevis
NP_001080870
273
29899
T82
V
G
N
G
T
K
T
T
Y
E
G
L
V
Q
S
Zebra Danio
Brachydanio rerio
NP_998370
265
29164
N76
G
D
A
G
G
V
K
N
A
G
L
I
Q
Q
E
Tiger Blowfish
Takifugu rubipres
NP_001033033
272
30118
V84
G
G
I
S
G
A
G
V
I
Q
I
D
N
K
K
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784873
183
20114
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
98.9
66.4
N.A.
91.7
91
N.A.
54.1
52
59.2
48.7
42.9
N.A.
N.A.
N.A.
30.3
Protein Similarity:
100
87.7
99.2
68.6
N.A.
95.6
95.6
N.A.
63.9
63.7
72.9
66.7
59.9
N.A.
N.A.
N.A.
42.6
P-Site Identity:
100
0
100
86.6
N.A.
93.3
93.3
N.A.
26.6
13.3
13.3
6.6
13.3
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
100
93.3
N.A.
93.3
93.3
N.A.
33.3
20
33.3
26.6
26.6
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
0
0
9
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
9
0
0
0
42
0
0
% C
% Asp:
0
9
0
42
0
0
9
0
0
9
0
17
9
9
0
% D
% Glu:
0
9
9
9
0
9
0
0
0
9
9
0
0
0
67
% E
% Phe:
0
0
9
0
0
0
0
0
0
42
0
0
0
0
0
% F
% Gly:
17
67
0
17
17
0
9
9
0
25
9
9
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
25
0
42
0
9
9
0
0
9
% I
% Lys:
9
0
0
9
0
9
17
0
0
0
0
0
0
9
9
% K
% Leu:
0
0
0
9
0
0
0
9
9
0
9
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
9
0
0
0
0
9
0
0
% N
% Pro:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
42
0
0
0
0
0
0
0
9
9
0
0
9
17
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
42
0
0
50
0
% R
% Ser:
0
9
34
9
17
0
17
9
0
0
9
0
0
0
9
% S
% Thr:
0
0
0
0
59
9
9
9
0
0
0
0
9
0
0
% T
% Val:
9
0
0
0
0
9
9
9
0
0
9
50
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
42
0
42
9
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _