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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COX5A All Species: 43.03
Human Site: Y80 Identified Species: 67.62
UniProt: P20674 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20674 NP_004246.2 150 16762 Y80 G I N T L V T Y D M V P E P K
Chimpanzee Pan troglodytes B0VYX1 150 16630 Y80 G I N T L V T Y D M V P E P K
Rhesus Macaque Macaca mulatta Q53CF8 150 16651 Y80 G I N T L V T Y D L V P E P K
Dog Lupus familis XP_853952 151 16625 Y81 G M N T L V G Y D L V P E P K
Cat Felis silvestris
Mouse Mus musculus P12787 146 16083 Y76 G M N T L V G Y D L V P E P K
Rat Rattus norvegicus P11240 146 16111 Y76 G M N T L V G Y D L V P E P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511903 376 41939 Y306 G M N T L V G Y D L V P E P K
Chicken Gallus gallus
Frog Xenopus laevis NP_001085392 148 16448 Y78 G M N T L I G Y D L V P E P K
Zebra Danio Brachydanio rerio XP_700576 172 19236 Y102 G M N T L I G Y D L V P E P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q94514 149 16604 P74 G M D L V P S P K I I E A G L
Honey Bee Apis mellifera XP_392368 152 17602 P76 A M D L V P D P S I I C A A L
Nematode Worm Caenorhab. elegans P55954 174 20092 Y72 A L S E L H D Y D V I P D P K
Sea Urchin Strong. purpuratus XP_784558 149 16879 H73 G L N E L H G H D L V P E P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P00427 148 17323 Y79 V L N N C F S Y D L V P A P A
Red Bread Mold Neurospora crassa Q01359 148 16785 Y78 N L N N A F A Y D L V P S P S
Conservation
Percent
Protein Identity: 100 98 96 86.7 N.A. 86 85.3 N.A. 35.6 N.A. 78 60.4 N.A. 48.6 48 36.7 59.3
Protein Similarity: 100 98 96.6 90 N.A. 88.6 88 N.A. 36.7 N.A. 85.3 70.9 N.A. 64 67.7 54 70.6
P-Site Identity: 100 100 93.3 80 N.A. 80 80 N.A. 80 N.A. 73.3 73.3 N.A. 6.6 0 40 60
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 93.3 N.A. 93.3 93.3 N.A. 46.6 33.3 73.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.3 32
Protein Similarity: N.A. N.A. N.A. N.A. 50.6 48.6
P-Site Identity: N.A. N.A. N.A. N.A. 40 40
P-Site Similarity: N.A. N.A. N.A. N.A. 60 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 0 7 0 7 0 0 0 0 0 20 7 7 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 14 0 0 0 14 0 87 0 0 0 7 0 0 % D
% Glu: 0 0 0 14 0 0 0 0 0 0 0 7 67 0 0 % E
% Phe: 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 % F
% Gly: 74 0 0 0 0 0 47 0 0 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 14 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 20 0 0 0 14 0 0 0 14 20 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 74 % K
% Leu: 0 27 0 14 74 0 0 0 0 67 0 0 0 0 14 % L
% Met: 0 54 0 0 0 0 0 0 0 14 0 0 0 0 0 % M
% Asn: 7 0 80 14 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 14 0 14 0 0 0 87 0 87 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 7 0 0 0 14 0 7 0 0 0 7 0 7 % S
% Thr: 0 0 0 60 0 0 20 0 0 0 0 0 0 0 0 % T
% Val: 7 0 0 0 14 47 0 0 0 7 80 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 80 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _