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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAK All Species: 11.21
Human Site: S363 Identified Species: 20.56
UniProt: P20794 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20794 NP_005897.1 623 70581 S363 Q Q P P K Q Q S Q E K P P Q T
Chimpanzee Pan troglodytes XP_001167620 623 70608 S363 Q Q P P K Q Q S Q E K P P Q T
Rhesus Macaque Macaca mulatta XP_001088297 623 70579 S363 Q Q P P K Q Q S Q Q K P P Q T
Dog Lupus familis XP_535886 623 70299 G363 Q P A P K Q P G Q Q K R P Q T
Cat Felis silvestris
Mouse Mus musculus Q04859 622 70031 Q362 T H P P P K Q Q G H Q K P P Q
Rat Rattus norvegicus P20793 622 69906 Q362 V Q P P P K Q Q G H H K Q P Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514363 623 70669 Q362 V Q Q I P K Q Q P Q Q K Q Q Q
Chicken Gallus gallus XP_418948 628 70589 Q368 Q Q V S K Q Q Q T Q A Q P F F
Frog Xenopus laevis P23437 297 33852 D38 A L K K I R L D T E T E G V P
Zebra Danio Brachydanio rerio NP_956240 633 71283 L372 G E N S L M G L K N G R R R W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392924 569 65790 K310 Q R D F V I N K V N L P P P V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200813 576 64528 S316 R Q A P N Q N S A K R R V L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P43294 443 50877 Y184 V L L Q S S L Y T P A V D M W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97.7 91.4 N.A. 84.1 85 N.A. 76.2 71.9 21.8 59.8 N.A. N.A. 46.2 N.A. 49.4
Protein Similarity: 100 99.5 99.3 93.7 N.A. 90.3 91.1 N.A. 85.5 81.5 33 71.8 N.A. N.A. 60.5 N.A. 64.3
P-Site Identity: 100 100 93.3 60 N.A. 26.6 26.6 N.A. 20 40 6.6 0 N.A. N.A. 20 N.A. 26.6
P-Site Similarity: 100 100 100 66.6 N.A. 40 33.3 N.A. 40 46.6 13.3 20 N.A. N.A. 26.6 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 34.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 50.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 0 0 0 0 0 8 0 16 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 8 0 0 0 0 8 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 24 0 8 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 8 % F
% Gly: 8 0 0 0 0 0 8 8 16 0 8 0 8 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 16 8 0 0 0 0 % H
% Ile: 0 0 0 8 8 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 8 39 24 0 8 8 8 31 24 0 0 0 % K
% Leu: 0 16 8 0 8 0 16 8 0 0 8 0 0 8 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 8 0 8 0 16 0 0 16 0 0 0 0 0 % N
% Pro: 0 8 39 54 24 0 8 0 8 8 0 31 54 24 8 % P
% Gln: 47 54 8 8 0 47 54 31 31 31 16 8 16 39 24 % Q
% Arg: 8 8 0 0 0 8 0 0 0 0 8 24 8 8 0 % R
% Ser: 0 0 0 16 8 8 0 31 0 0 0 0 0 0 0 % S
% Thr: 8 0 0 0 0 0 0 0 24 0 8 0 0 0 31 % T
% Val: 24 0 8 0 8 0 0 0 8 0 0 8 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _