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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAK
All Species:
12.73
Human Site:
S391
Identified Species:
23.33
UniProt:
P20794
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20794
NP_005897.1
623
70581
S391
N
G
T
L
S
H
K
S
G
R
R
R
W
G
Q
Chimpanzee
Pan troglodytes
XP_001167620
623
70608
S391
N
G
T
L
S
H
K
S
G
R
R
R
W
G
Q
Rhesus Macaque
Macaca mulatta
XP_001088297
623
70579
S391
N
G
T
L
S
H
K
S
G
R
R
R
W
G
Q
Dog
Lupus familis
XP_535886
623
70299
S391
N
G
A
L
G
H
K
S
A
R
R
R
W
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q04859
622
70031
K390
S
V
S
A
L
G
H
K
G
A
R
R
R
W
G
Rat
Rattus norvegicus
P20793
622
69906
K390
P
V
S
T
V
G
H
K
G
A
R
R
R
W
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514363
623
70669
N390
N
G
A
V
G
Y
K
N
G
R
R
R
W
G
Q
Chicken
Gallus gallus
XP_418948
628
70589
V396
A
G
P
Q
N
G
T
V
G
P
K
S
C
R
R
Frog
Xenopus laevis
P23437
297
33852
L66
N
H
P
N
I
V
K
L
L
D
V
I
H
T
E
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
A400
S
D
C
S
D
T
A
A
S
L
S
K
K
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
M338
G
S
R
A
Q
E
K
M
I
Q
P
K
E
Q
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
P344
P
K
R
D
N
A
Q
P
K
D
S
M
D
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
E212
P
L
F
P
G
E
S
E
I
D
Q
L
Y
K
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.7
91.4
N.A.
84.1
85
N.A.
76.2
71.9
21.8
59.8
N.A.
N.A.
46.2
N.A.
49.4
Protein Similarity:
100
99.5
99.3
93.7
N.A.
90.3
91.1
N.A.
85.5
81.5
33
71.8
N.A.
N.A.
60.5
N.A.
64.3
P-Site Identity:
100
100
100
80
N.A.
20
20
N.A.
66.6
13.3
13.3
0
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
100
80
N.A.
33.3
26.6
N.A.
86.6
33.3
20
20
N.A.
N.A.
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
16
0
8
8
8
8
16
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
0
8
8
0
0
0
0
24
0
0
8
8
0
% D
% Glu:
0
0
0
0
0
16
0
8
0
0
0
0
8
0
16
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
47
0
0
24
24
0
0
54
0
0
0
0
39
16
% G
% His:
0
8
0
0
0
31
16
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
16
0
0
8
0
0
8
% I
% Lys:
0
8
0
0
0
0
54
16
8
0
8
16
8
8
0
% K
% Leu:
0
8
0
31
8
0
0
8
8
8
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
47
0
0
8
16
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
24
0
16
8
0
0
0
8
0
8
8
0
0
8
0
% P
% Gln:
0
0
0
8
8
0
8
0
0
8
8
0
0
8
39
% Q
% Arg:
0
0
16
0
0
0
0
0
0
39
54
54
16
8
8
% R
% Ser:
16
8
16
8
24
0
8
31
8
0
16
8
0
0
8
% S
% Thr:
0
0
24
8
0
8
8
0
0
0
0
0
0
8
0
% T
% Val:
0
16
0
8
8
8
0
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
39
16
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _