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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAK
All Species:
17.88
Human Site:
S436
Identified Species:
32.78
UniProt:
P20794
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20794
NP_005897.1
623
70581
S436
K
E
K
R
K
K
D
S
P
F
R
L
P
E
P
Chimpanzee
Pan troglodytes
XP_001167620
623
70608
S436
K
E
K
R
K
K
D
S
P
F
R
L
P
E
P
Rhesus Macaque
Macaca mulatta
XP_001088297
623
70579
S436
K
D
K
R
K
K
D
S
P
F
R
L
P
E
P
Dog
Lupus familis
XP_535886
623
70299
S436
K
E
K
R
K
K
D
S
P
F
R
L
P
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q04859
622
70031
P435
K
E
K
K
K
E
S
P
F
R
F
P
D
S
G
Rat
Rattus norvegicus
P20793
622
69906
E435
F
K
E
K
K
K
K
E
S
P
F
R
F
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514363
623
70669
S435
K
E
K
K
A
K
D
S
S
F
S
D
P
D
P
Chicken
Gallus gallus
XP_418948
628
70589
K441
I
A
L
L
K
E
K
K
N
K
E
C
P
F
S
Frog
Xenopus laevis
P23437
297
33852
L111
V
K
S
Y
L
F
Q
L
L
Q
G
L
A
F
C
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
S445
S
R
L
N
Q
S
D
S
S
H
Q
S
T
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
N383
G
S
K
I
V
P
E
N
V
N
S
K
L
V
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
V389
K
W
E
T
G
K
K
V
E
D
S
W
D
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
L257
Q
T
R
I
A
D
L
L
P
N
A
A
P
E
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.7
91.4
N.A.
84.1
85
N.A.
76.2
71.9
21.8
59.8
N.A.
N.A.
46.2
N.A.
49.4
Protein Similarity:
100
99.5
99.3
93.7
N.A.
90.3
91.1
N.A.
85.5
81.5
33
71.8
N.A.
N.A.
60.5
N.A.
64.3
P-Site Identity:
100
100
93.3
93.3
N.A.
26.6
13.3
N.A.
60
13.3
6.6
13.3
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
40
33.3
N.A.
73.3
20
13.3
26.6
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
16
0
0
0
0
0
8
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% C
% Asp:
0
8
0
0
0
8
47
0
0
8
0
8
16
16
0
% D
% Glu:
0
39
16
0
0
16
8
8
8
0
8
0
0
39
8
% E
% Phe:
8
0
0
0
0
8
0
0
8
39
16
0
8
16
8
% F
% Gly:
8
0
0
0
8
0
0
0
0
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
54
16
54
24
54
54
24
8
0
8
0
8
0
0
0
% K
% Leu:
0
0
16
8
8
0
8
16
8
0
0
39
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
8
16
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
8
39
8
0
8
54
8
39
% P
% Gln:
8
0
0
0
8
0
8
0
0
8
8
0
0
0
0
% Q
% Arg:
0
8
8
31
0
0
0
0
0
8
31
8
0
0
0
% R
% Ser:
8
8
8
0
0
8
8
47
24
0
24
8
0
16
24
% S
% Thr:
0
8
0
8
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
8
0
0
0
8
0
0
8
8
0
0
0
0
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _