KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAK
All Species:
12.73
Human Site:
S446
Identified Species:
23.33
UniProt:
P20794
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20794
NP_005897.1
623
70581
S446
R
L
P
E
P
V
P
S
G
S
N
H
S
T
G
Chimpanzee
Pan troglodytes
XP_001167620
623
70608
S446
R
L
P
E
P
V
P
S
G
S
N
H
S
T
G
Rhesus Macaque
Macaca mulatta
XP_001088297
623
70579
S446
R
L
P
E
P
V
P
S
G
A
S
H
S
T
G
Dog
Lupus familis
XP_535886
623
70299
S446
R
L
P
E
S
V
P
S
G
S
Y
H
S
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q04859
622
70031
V445
F
P
D
S
G
L
P
V
S
N
H
F
K
G
E
Rat
Rattus norvegicus
P20793
622
69906
L445
F
R
F
P
E
A
G
L
P
V
S
N
H
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514363
623
70669
A445
S
D
P
D
P
A
P
A
S
C
N
Q
A
R
G
Chicken
Gallus gallus
XP_418948
628
70589
E451
E
C
P
F
S
V
P
E
P
K
A
S
H
C
I
Frog
Xenopus laevis
P23437
297
33852
H121
G
L
A
F
C
H
S
H
R
V
L
H
R
D
L
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
Q455
Q
S
T
S
S
A
R
Q
H
Y
L
R
Q
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
V393
S
K
L
V
P
E
R
V
Y
K
E
N
R
A
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
E399
S
W
D
D
F
D
L
E
G
S
R
G
F
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
L267
A
A
P
E
A
I
D
L
I
N
R
L
C
S
W
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.7
91.4
N.A.
84.1
85
N.A.
76.2
71.9
21.8
59.8
N.A.
N.A.
46.2
N.A.
49.4
Protein Similarity:
100
99.5
99.3
93.7
N.A.
90.3
91.1
N.A.
85.5
81.5
33
71.8
N.A.
N.A.
60.5
N.A.
64.3
P-Site Identity:
100
100
86.6
80
N.A.
6.6
0
N.A.
33.3
20
13.3
0
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
100
100
100
80
N.A.
26.6
13.3
N.A.
53.3
20
13.3
13.3
N.A.
N.A.
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
8
24
0
8
0
8
8
0
8
16
0
% A
% Cys:
0
8
0
0
8
0
0
0
0
8
0
0
8
8
0
% C
% Asp:
0
8
16
16
0
8
8
0
0
0
0
0
0
8
0
% D
% Glu:
8
0
0
39
8
8
0
16
0
0
8
0
0
0
8
% E
% Phe:
16
0
8
16
8
0
0
0
0
0
0
8
8
0
0
% F
% Gly:
8
0
0
0
8
0
8
0
39
0
0
8
0
16
47
% G
% His:
0
0
0
0
0
8
0
8
8
0
8
39
16
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
8
% I
% Lys:
0
8
0
0
0
0
0
0
0
16
0
0
8
0
8
% K
% Leu:
0
39
8
0
0
8
8
16
0
0
16
8
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
16
24
16
0
0
8
% N
% Pro:
0
8
54
8
39
0
54
0
16
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% Q
% Arg:
31
8
0
0
0
0
16
0
8
0
16
8
16
8
8
% R
% Ser:
24
8
0
16
24
0
8
31
16
31
16
8
31
16
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
0
24
0
% T
% Val:
0
0
0
8
0
39
0
16
0
16
0
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
8
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _