KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAK
All Species:
12.73
Human Site:
S466
Identified Species:
23.33
UniProt:
P20794
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20794
NP_005897.1
623
70581
S466
P
A
V
T
S
L
K
S
D
S
E
L
S
T
A
Chimpanzee
Pan troglodytes
XP_001167620
623
70608
S466
P
A
V
T
S
L
K
S
D
S
E
L
S
T
A
Rhesus Macaque
Macaca mulatta
XP_001088297
623
70579
S466
P
A
V
I
S
L
K
S
D
S
E
L
S
T
A
Dog
Lupus familis
XP_535886
623
70299
S466
P
A
A
I
S
L
K
S
D
S
E
L
S
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q04859
622
70031
D465
A
S
V
S
L
K
S
D
P
N
L
S
T
A
S
Rat
Rattus norvegicus
P20793
622
69906
D465
L
H
A
S
L
K
S
D
T
N
L
S
T
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514363
623
70669
N465
P
A
G
A
F
L
K
N
D
T
D
L
S
T
A
Chicken
Gallus gallus
XP_418948
628
70589
D471
N
K
V
L
M
R
N
D
S
G
R
S
N
T
S
Frog
Xenopus laevis
P23437
297
33852
I141
L
I
N
S
D
G
A
I
K
L
A
D
F
G
L
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
L475
I
S
K
N
T
Q
S
L
S
S
K
E
S
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
W413
L
P
E
N
P
R
N
W
V
L
P
A
W
N
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
G419
K
K
I
G
G
M
K
G
K
A
L
P
T
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
N287
P
T
A
D
E
A
L
N
H
P
F
F
S
M
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.7
91.4
N.A.
84.1
85
N.A.
76.2
71.9
21.8
59.8
N.A.
N.A.
46.2
N.A.
49.4
Protein Similarity:
100
99.5
99.3
93.7
N.A.
90.3
91.1
N.A.
85.5
81.5
33
71.8
N.A.
N.A.
60.5
N.A.
64.3
P-Site Identity:
100
100
93.3
86.6
N.A.
6.6
0
N.A.
60
13.3
0
13.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
40
26.6
N.A.
80
26.6
6.6
33.3
N.A.
N.A.
0
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
39
24
8
0
8
8
0
0
8
8
8
0
16
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
0
24
39
0
8
8
0
0
0
% D
% Glu:
0
0
8
0
8
0
0
0
0
0
31
8
0
0
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
8
8
8
0
0
% F
% Gly:
0
0
8
8
8
8
0
8
0
8
0
0
0
8
8
% G
% His:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
8
8
16
0
0
0
8
0
0
0
0
0
8
0
% I
% Lys:
8
16
8
0
0
16
47
0
16
0
8
0
0
0
0
% K
% Leu:
24
0
0
8
16
39
8
8
0
16
24
39
0
0
8
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
8
16
0
0
16
16
0
16
0
0
8
8
0
% N
% Pro:
47
8
0
0
8
0
0
0
8
8
8
8
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% Q
% Arg:
0
0
0
0
0
16
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
16
0
24
31
0
24
31
16
39
0
24
54
0
24
% S
% Thr:
0
8
0
16
8
0
0
0
8
8
0
0
24
47
0
% T
% Val:
0
0
39
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _