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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAK All Species: 23.64
Human Site: S471 Identified Species: 43.33
UniProt: P20794 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20794 NP_005897.1 623 70581 S471 L K S D S E L S T A P T S K Q
Chimpanzee Pan troglodytes XP_001167620 623 70608 S471 L K S D S E L S T A P T S K Q
Rhesus Macaque Macaca mulatta XP_001088297 623 70579 S471 L K S D S E L S T A P T S K Q
Dog Lupus familis XP_535886 623 70299 S471 L K S D S E L S T A S T A K Q
Cat Felis silvestris
Mouse Mus musculus Q04859 622 70031 T470 K S D P N L S T A S T A K Q Y
Rat Rattus norvegicus P20793 622 69906 T470 K S D T N L S T A S T A K Q Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514363 623 70669 S470 L K N D T D L S T A S T A K Q
Chicken Gallus gallus XP_418948 628 70589 N476 R N D S G R S N T S A K Q Y Y
Frog Xenopus laevis P23437 297 33852 F146 G A I K L A D F G L A R A F G
Zebra Danio Brachydanio rerio NP_956240 633 71283 S480 Q S L S S K E S Q Q D F W D T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392924 569 65790 W418 R N W V L P A W N E P A P I N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200813 576 64528 T424 M K G K A L P T I G A G N A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P43294 443 50877 S292 A L N H P F F S M A T Q A S Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97.7 91.4 N.A. 84.1 85 N.A. 76.2 71.9 21.8 59.8 N.A. N.A. 46.2 N.A. 49.4
Protein Similarity: 100 99.5 99.3 93.7 N.A. 90.3 91.1 N.A. 85.5 81.5 33 71.8 N.A. N.A. 60.5 N.A. 64.3
P-Site Identity: 100 100 100 86.6 N.A. 0 0 N.A. 66.6 6.6 0 13.3 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 26.6 26.6 N.A. 93.3 20 6.6 20 N.A. N.A. 6.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 34.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 50.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 8 8 8 0 16 47 24 24 31 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 24 39 0 8 8 0 0 0 8 0 0 8 0 % D
% Glu: 0 0 0 0 0 31 8 0 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 8 8 0 0 0 8 0 8 0 % F
% Gly: 8 0 8 0 8 0 0 0 8 8 0 8 0 0 8 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 8 0 0 0 0 8 0 % I
% Lys: 16 47 0 16 0 8 0 0 0 0 0 8 16 39 0 % K
% Leu: 39 8 8 0 16 24 39 0 0 8 0 0 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 16 16 0 16 0 0 8 8 0 0 0 8 0 8 % N
% Pro: 0 0 0 8 8 8 8 0 0 0 31 0 8 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 8 8 0 8 8 16 39 % Q
% Arg: 16 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % R
% Ser: 0 24 31 16 39 0 24 54 0 24 16 0 24 8 0 % S
% Thr: 0 0 0 8 8 0 0 24 47 0 24 39 0 0 8 % T
% Val: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 8 0 0 0 0 8 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 31 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _