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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAK
All Species:
16.67
Human Site:
S496
Identified Species:
30.56
UniProt:
P20794
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20794
NP_005897.1
623
70581
S496
G
V
N
P
K
K
V
S
L
I
A
S
G
K
E
Chimpanzee
Pan troglodytes
XP_001167620
623
70608
S496
G
V
N
P
K
K
V
S
L
I
A
S
G
K
E
Rhesus Macaque
Macaca mulatta
XP_001088297
623
70579
S496
G
V
N
P
K
N
V
S
L
M
A
S
G
K
E
Dog
Lupus familis
XP_535886
623
70299
S496
G
V
N
P
K
T
V
S
L
V
A
G
G
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q04859
622
70031
L495
V
N
P
K
N
V
S
L
V
A
G
G
K
D
I
Rat
Rattus norvegicus
P20793
622
69906
L495
V
N
P
K
N
V
S
L
V
A
G
G
K
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514363
623
70669
S495
G
V
N
P
K
N
V
S
L
L
A
P
G
K
E
Chicken
Gallus gallus
XP_418948
628
70589
V501
N
P
K
T
V
S
L
V
A
V
N
K
E
G
S
Frog
Xenopus laevis
P23437
297
33852
P171
V
T
L
W
Y
R
A
P
E
I
L
L
G
C
K
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
R505
I
G
G
A
P
M
S
R
I
S
P
G
N
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
Q443
G
R
K
V
S
G
K
Q
H
Y
F
S
L
A
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
P449
D
D
D
F
L
K
S
P
T
K
H
R
V
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
L317
N
M
A
A
L
P
N
L
E
L
N
L
W
D
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.7
91.4
N.A.
84.1
85
N.A.
76.2
71.9
21.8
59.8
N.A.
N.A.
46.2
N.A.
49.4
Protein Similarity:
100
99.5
99.3
93.7
N.A.
90.3
91.1
N.A.
85.5
81.5
33
71.8
N.A.
N.A.
60.5
N.A.
64.3
P-Site Identity:
100
100
86.6
73.3
N.A.
0
0
N.A.
80
0
13.3
0
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
6.6
6.6
N.A.
86.6
13.3
26.6
6.6
N.A.
N.A.
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
16
0
0
8
0
8
16
39
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
8
8
0
0
0
0
0
0
0
0
0
0
24
8
% D
% Glu:
0
0
0
0
0
0
0
0
16
0
0
0
8
0
31
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
0
8
8
% F
% Gly:
47
8
8
0
0
8
0
0
0
0
16
31
47
16
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
24
0
0
0
0
16
% I
% Lys:
0
0
16
16
39
24
8
0
0
8
0
8
16
39
8
% K
% Leu:
0
0
8
0
16
0
8
24
39
16
8
16
8
0
0
% L
% Met:
0
8
0
0
0
8
0
0
0
8
0
0
0
0
0
% M
% Asn:
16
16
39
0
16
16
8
0
0
0
16
0
8
0
0
% N
% Pro:
0
8
16
39
8
8
0
16
0
0
8
8
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
0
8
0
0
0
8
0
0
8
% R
% Ser:
0
0
0
0
8
8
31
39
0
8
0
31
0
0
8
% S
% Thr:
0
8
0
8
0
8
0
0
8
0
0
0
0
0
0
% T
% Val:
24
39
0
8
8
16
39
8
16
16
0
0
8
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _