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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAK All Species: 5.15
Human Site: S530 Identified Species: 9.44
UniProt: P20794 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20794 NP_005897.1 623 70581 S530 A E L A F K R S N A G N L G S
Chimpanzee Pan troglodytes XP_001167620 623 70608 R530 A E L A F K R R N A G N L G S
Rhesus Macaque Macaca mulatta XP_001088297 623 70579 S530 A E L A F K R S N A G N L G S
Dog Lupus familis XP_535886 623 70299 N530 A E L A F K R N N A G N L G S
Cat Felis silvestris
Mouse Mus musculus Q04859 622 70031 N529 D L S F K R S N A A G N L G S
Rat Rattus norvegicus P20793 622 69906 N529 D L A F K R S N A A G N L G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514363 623 70669 N529 A G L S F N K N N T G S L E G
Chicken Gallus gallus XP_418948 628 70589 T535 L H F N R N N T G N S D F V G
Frog Xenopus laevis P23437 297 33852 G205 T R R A L F P G D S E I D Q L
Zebra Danio Brachydanio rerio NP_956240 633 71283 Q539 G S V G Q R I Q L A P L G H Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392924 569 65790 L477 K P R L M R N L V G Q S V E K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200813 576 64528 F483 S A S S A K Q F Y M G K A R Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P43294 443 50877 N351 P K L E M L R N V S Q D M S E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97.7 91.4 N.A. 84.1 85 N.A. 76.2 71.9 21.8 59.8 N.A. N.A. 46.2 N.A. 49.4
Protein Similarity: 100 99.5 99.3 93.7 N.A. 90.3 91.1 N.A. 85.5 81.5 33 71.8 N.A. N.A. 60.5 N.A. 64.3
P-Site Identity: 100 93.3 100 93.3 N.A. 40 40 N.A. 40 0 6.6 6.6 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 93.3 100 100 N.A. 53.3 53.3 N.A. 66.6 13.3 20 20 N.A. N.A. 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 34.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 50.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 8 8 39 8 0 0 0 16 54 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 0 0 0 0 0 0 0 8 0 0 16 8 0 0 % D
% Glu: 0 31 0 8 0 0 0 0 0 0 8 0 0 16 8 % E
% Phe: 0 0 8 16 39 8 0 8 0 0 0 0 8 0 0 % F
% Gly: 8 8 0 8 0 0 0 8 8 8 62 0 8 47 16 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % I
% Lys: 8 8 0 0 16 39 8 0 0 0 0 8 0 0 8 % K
% Leu: 8 16 47 8 8 8 0 8 8 0 0 8 54 0 8 % L
% Met: 0 0 0 0 16 0 0 0 0 8 0 0 8 0 0 % M
% Asn: 0 0 0 8 0 16 16 39 39 8 0 47 0 0 0 % N
% Pro: 8 8 0 0 0 0 8 0 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 8 8 0 0 16 0 0 8 8 % Q
% Arg: 0 8 16 0 8 31 39 8 0 0 0 0 0 8 0 % R
% Ser: 8 8 16 16 0 0 16 16 0 16 8 16 0 8 47 % S
% Thr: 8 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % T
% Val: 0 0 8 0 0 0 0 0 16 0 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _