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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAK
All Species:
22.42
Human Site:
S586
Identified Species:
41.11
UniProt:
P20794
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20794
NP_005897.1
623
70581
S586
K
T
G
R
G
Q
F
S
G
R
T
Y
N
P
T
Chimpanzee
Pan troglodytes
XP_001167620
623
70608
S586
K
T
G
R
G
Q
F
S
G
R
T
Y
N
P
T
Rhesus Macaque
Macaca mulatta
XP_001088297
623
70579
S586
K
T
G
R
G
Q
F
S
G
R
T
Y
N
P
T
Dog
Lupus familis
XP_535886
623
70299
S586
K
P
S
R
G
Q
F
S
G
P
T
Y
N
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q04859
622
70031
S585
K
T
G
R
G
Q
F
S
G
R
T
Y
N
P
T
Rat
Rattus norvegicus
P20793
622
69906
S585
K
T
G
R
G
Q
F
S
G
R
T
Y
N
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514363
623
70669
F585
T
Q
T
G
R
A
Q
F
P
G
P
A
Y
S
S
Chicken
Gallus gallus
XP_418948
628
70589
L591
T
K
A
A
R
A
Q
L
A
G
P
T
Y
N
S
Frog
Xenopus laevis
P23437
297
33852
D261
P
L
D
E
D
G
R
D
L
L
A
Q
M
L
Q
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
K595
R
A
E
R
T
Q
L
K
G
T
S
Y
S
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
I533
S
V
Y
G
T
Q
N
I
K
N
T
D
K
G
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
T539
G
Y
N
E
P
W
K
T
T
T
K
A
G
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
V407
S
P
M
Q
Q
H
T
V
G
P
P
Q
S
S
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.7
91.4
N.A.
84.1
85
N.A.
76.2
71.9
21.8
59.8
N.A.
N.A.
46.2
N.A.
49.4
Protein Similarity:
100
99.5
99.3
93.7
N.A.
90.3
91.1
N.A.
85.5
81.5
33
71.8
N.A.
N.A.
60.5
N.A.
64.3
P-Site Identity:
100
100
100
80
N.A.
100
100
N.A.
0
0
0
26.6
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
100
100
N.A.
6.6
6.6
0
46.6
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
16
0
0
8
0
8
16
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
8
0
0
0
8
0
0
0
% D
% Glu:
0
0
8
16
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
47
8
0
0
0
0
0
0
0
% F
% Gly:
8
0
39
16
47
8
0
0
62
16
0
0
8
8
8
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
47
8
0
0
0
0
8
8
8
0
8
0
8
0
0
% K
% Leu:
0
8
0
0
0
0
8
8
8
8
0
0
0
8
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
0
8
0
0
47
8
0
% N
% Pro:
8
16
0
0
8
0
0
0
8
16
24
0
0
47
0
% P
% Gln:
0
8
0
8
8
62
16
0
0
0
0
16
0
0
8
% Q
% Arg:
8
0
0
54
16
0
8
0
0
39
0
0
0
0
0
% R
% Ser:
16
0
8
0
0
0
0
47
0
0
8
0
16
16
16
% S
% Thr:
16
39
8
0
16
0
8
8
8
16
54
8
0
0
62
% T
% Val:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
0
0
0
0
54
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _