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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAK All Species: 36.36
Human Site: T162 Identified Species: 66.67
UniProt: P20794 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20794 NP_005897.1 623 70581 T162 P Y T D Y V S T R W Y R A P E
Chimpanzee Pan troglodytes XP_001167620 623 70608 T162 P Y T D Y V S T R W Y R A P E
Rhesus Macaque Macaca mulatta XP_001088297 623 70579 T162 P Y T D Y V S T R W Y R A P E
Dog Lupus familis XP_535886 623 70299 T162 P Y T D Y V S T R W Y R A P E
Cat Felis silvestris
Mouse Mus musculus Q04859 622 70031 T162 P Y T D Y V S T R W Y R A P E
Rat Rattus norvegicus P20793 622 69906 T162 P Y T D Y V S T R W Y R A P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514363 623 70669 T162 P Y T D Y V S T R W Y R A P E
Chicken Gallus gallus XP_418948 628 70589 T162 P Y T D Y V S T R W Y R A P E
Frog Xenopus laevis P23437 297 33852
Zebra Danio Brachydanio rerio NP_956240 633 71283 T163 P Y T D Y V S T R W Y R A P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392924 569 65790 K118 Q G L A F M H K H G F F H R D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200813 576 64528 R124 H K N G F F H R D M K P E N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P43294 443 50877
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97.7 91.4 N.A. 84.1 85 N.A. 76.2 71.9 21.8 59.8 N.A. N.A. 46.2 N.A. 49.4
Protein Similarity: 100 99.5 99.3 93.7 N.A. 90.3 91.1 N.A. 85.5 81.5 33 71.8 N.A. N.A. 60.5 N.A. 64.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 0 100 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 0 100 N.A. N.A. 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 34.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 50.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 0 0 0 70 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 70 0 0 0 0 8 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 70 % E
% Phe: 0 0 0 0 16 8 0 0 0 0 8 8 0 0 0 % F
% Gly: 0 8 0 8 0 0 0 0 0 8 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 16 0 8 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 0 8 0 0 8 0 0 0 0 % K
% Leu: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 70 0 0 0 0 0 0 0 0 0 0 8 0 70 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 8 70 0 0 70 0 8 0 % R
% Ser: 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 70 0 0 0 0 70 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 70 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 % W
% Tyr: 0 70 0 0 70 0 0 0 0 0 70 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _