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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAK
All Species:
13.33
Human Site:
T399
Identified Species:
24.44
UniProt:
P20794
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20794
NP_005897.1
623
70581
T399
G
R
R
R
W
G
Q
T
I
F
K
S
G
D
S
Chimpanzee
Pan troglodytes
XP_001167620
623
70608
T399
G
R
R
R
W
G
Q
T
I
F
K
S
G
D
S
Rhesus Macaque
Macaca mulatta
XP_001088297
623
70579
T399
G
R
R
R
W
G
Q
T
V
F
K
S
G
D
S
Dog
Lupus familis
XP_535886
623
70299
T399
A
R
R
R
W
G
Q
T
V
F
K
S
G
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q04859
622
70031
Q398
G
A
R
R
R
W
G
Q
T
V
F
K
S
G
D
Rat
Rattus norvegicus
P20793
622
69906
Q398
G
A
R
R
R
W
G
Q
T
V
F
K
S
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514363
623
70669
N398
G
R
R
R
W
G
Q
N
L
F
K
T
D
D
S
Chicken
Gallus gallus
XP_418948
628
70589
R404
G
P
K
S
C
R
R
R
W
G
Q
T
L
I
K
Frog
Xenopus laevis
P23437
297
33852
N74
L
D
V
I
H
T
E
N
K
L
Y
L
V
F
E
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
K408
S
L
S
K
K
P
S
K
G
P
E
E
E
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
K346
I
Q
P
K
E
Q
E
K
T
I
L
P
L
V
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
F352
K
D
S
M
D
D
F
F
A
N
L
G
K
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
C220
I
D
Q
L
Y
K
I
C
C
V
L
G
K
P
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.7
91.4
N.A.
84.1
85
N.A.
76.2
71.9
21.8
59.8
N.A.
N.A.
46.2
N.A.
49.4
Protein Similarity:
100
99.5
99.3
93.7
N.A.
90.3
91.1
N.A.
85.5
81.5
33
71.8
N.A.
N.A.
60.5
N.A.
64.3
P-Site Identity:
100
100
93.3
86.6
N.A.
20
20
N.A.
73.3
6.6
0
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
20
20
N.A.
86.6
33.3
6.6
20
N.A.
N.A.
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% C
% Asp:
0
24
0
0
8
8
0
0
0
0
0
0
8
39
24
% D
% Glu:
0
0
0
0
8
0
16
0
0
0
8
8
8
0
8
% E
% Phe:
0
0
0
0
0
0
8
8
0
39
16
0
0
8
0
% F
% Gly:
54
0
0
0
0
39
16
0
8
8
0
16
31
16
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
8
0
0
8
0
16
8
0
0
0
8
0
% I
% Lys:
8
0
8
16
8
8
0
16
8
0
39
16
16
8
16
% K
% Leu:
8
8
0
8
0
0
0
0
8
8
24
8
16
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
16
0
8
0
0
0
0
8
% N
% Pro:
0
8
8
0
0
8
0
0
0
8
0
8
0
8
0
% P
% Gln:
0
8
8
0
0
8
39
16
0
0
8
0
0
0
0
% Q
% Arg:
0
39
54
54
16
8
8
8
0
0
0
0
0
0
0
% R
% Ser:
8
0
16
8
0
0
8
0
0
0
0
31
16
8
39
% S
% Thr:
0
0
0
0
0
8
0
31
24
0
0
16
0
0
8
% T
% Val:
0
0
8
0
0
0
0
0
16
24
0
0
8
8
0
% V
% Trp:
0
0
0
0
39
16
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _