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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAK
All Species:
10.61
Human Site:
T452
Identified Species:
19.44
UniProt:
P20794
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20794
NP_005897.1
623
70581
T452
P
S
G
S
N
H
S
T
G
E
N
K
S
L
P
Chimpanzee
Pan troglodytes
XP_001167620
623
70608
T452
P
S
G
S
N
H
S
T
G
E
N
K
S
L
P
Rhesus Macaque
Macaca mulatta
XP_001088297
623
70579
T452
P
S
G
A
S
H
S
T
G
E
N
K
S
F
P
Dog
Lupus familis
XP_535886
623
70299
A452
P
S
G
S
Y
H
S
A
G
E
N
K
S
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q04859
622
70031
G451
P
V
S
N
H
F
K
G
E
N
R
N
L
H
A
Rat
Rattus norvegicus
P20793
622
69906
L451
G
L
P
V
S
N
H
L
K
G
E
N
R
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514363
623
70669
R451
P
A
S
C
N
Q
A
R
G
E
N
K
S
L
P
Chicken
Gallus gallus
XP_418948
628
70589
C457
P
E
P
K
A
S
H
C
I
Q
P
G
V
E
N
Frog
Xenopus laevis
P23437
297
33852
D127
S
H
R
V
L
H
R
D
L
K
P
Q
N
L
L
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
S461
R
Q
H
Y
L
R
Q
S
R
Y
M
P
G
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
A399
R
V
Y
K
E
N
R
A
N
W
N
V
N
Y
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
G405
L
E
G
S
R
G
F
G
G
T
S
A
K
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
S273
D
L
I
N
R
L
C
S
W
D
P
L
K
R
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.7
91.4
N.A.
84.1
85
N.A.
76.2
71.9
21.8
59.8
N.A.
N.A.
46.2
N.A.
49.4
Protein Similarity:
100
99.5
99.3
93.7
N.A.
90.3
91.1
N.A.
85.5
81.5
33
71.8
N.A.
N.A.
60.5
N.A.
64.3
P-Site Identity:
100
100
80
80
N.A.
6.6
0
N.A.
60
6.6
13.3
6.6
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
100
100
93.3
80
N.A.
20
13.3
N.A.
73.3
13.3
33.3
13.3
N.A.
N.A.
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
0
8
16
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
8
0
0
8
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% D
% Glu:
0
16
0
0
8
0
0
0
8
39
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
0
0
16
0
% F
% Gly:
8
0
39
0
0
8
0
16
47
8
0
8
8
0
0
% G
% His:
0
8
8
0
8
39
16
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
0
0
0
16
0
0
8
0
8
8
0
39
16
0
8
% K
% Leu:
8
16
0
0
16
8
0
8
8
0
0
8
8
39
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
16
24
16
0
0
8
8
47
16
16
8
8
% N
% Pro:
54
0
16
0
0
0
0
0
0
0
24
8
0
0
47
% P
% Gln:
0
8
0
0
0
8
8
0
0
8
0
8
0
0
0
% Q
% Arg:
16
0
8
0
16
8
16
8
8
0
8
0
8
8
0
% R
% Ser:
8
31
16
31
16
8
31
16
0
0
8
0
39
0
0
% S
% Thr:
0
0
0
0
0
0
0
24
0
8
0
0
0
8
0
% T
% Val:
0
16
0
16
0
0
0
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% W
% Tyr:
0
0
8
8
8
0
0
0
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _