KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAK
All Species:
26.06
Human Site:
Y590
Identified Species:
47.78
UniProt:
P20794
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20794
NP_005897.1
623
70581
Y590
G
Q
F
S
G
R
T
Y
N
P
T
A
K
N
L
Chimpanzee
Pan troglodytes
XP_001167620
623
70608
Y590
G
Q
F
S
G
R
T
Y
N
P
T
A
K
N
L
Rhesus Macaque
Macaca mulatta
XP_001088297
623
70579
Y590
G
Q
F
S
G
R
T
Y
N
P
T
A
K
N
L
Dog
Lupus familis
XP_535886
623
70299
Y590
G
Q
F
S
G
P
T
Y
N
P
T
A
K
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q04859
622
70031
Y589
G
Q
F
S
G
R
T
Y
N
P
T
A
K
N
L
Rat
Rattus norvegicus
P20793
622
69906
Y589
G
Q
F
S
G
R
T
Y
N
P
T
A
K
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514363
623
70669
A589
R
A
Q
F
P
G
P
A
Y
S
S
T
A
K
D
Chicken
Gallus gallus
XP_418948
628
70589
T595
R
A
Q
L
A
G
P
T
Y
N
S
A
K
N
M
Frog
Xenopus laevis
P23437
297
33852
Q265
D
G
R
D
L
L
A
Q
M
L
Q
Y
D
S
N
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
Y599
T
Q
L
K
G
T
S
Y
S
A
L
G
K
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
D537
T
Q
N
I
K
N
T
D
K
G
T
L
L
P
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
A543
P
W
K
T
T
T
K
A
G
V
T
N
T
F
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
Q411
Q
H
T
V
G
P
P
Q
S
S
G
F
T
M
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.7
91.4
N.A.
84.1
85
N.A.
76.2
71.9
21.8
59.8
N.A.
N.A.
46.2
N.A.
49.4
Protein Similarity:
100
99.5
99.3
93.7
N.A.
90.3
91.1
N.A.
85.5
81.5
33
71.8
N.A.
N.A.
60.5
N.A.
64.3
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
0
20
0
33.3
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
33.3
6.6
46.6
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
8
0
8
16
0
8
0
54
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
8
0
0
0
0
8
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
47
8
0
0
0
0
0
0
0
8
0
8
0
% F
% Gly:
47
8
0
0
62
16
0
0
8
8
8
8
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
8
0
8
0
8
0
0
0
62
8
0
% K
% Leu:
0
0
8
8
8
8
0
0
0
8
8
8
8
0
47
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
8
% M
% Asn:
0
0
8
0
0
8
0
0
47
8
0
8
0
62
8
% N
% Pro:
8
0
0
0
8
16
24
0
0
47
0
0
0
8
0
% P
% Gln:
8
62
16
0
0
0
0
16
0
0
8
0
0
0
0
% Q
% Arg:
16
0
8
0
0
39
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
47
0
0
8
0
16
16
16
0
0
8
16
% S
% Thr:
16
0
8
8
8
16
54
8
0
0
62
8
16
0
8
% T
% Val:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
16
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _