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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPN3
All Species:
18.18
Human Site:
S474
Identified Species:
50
UniProt:
P20807
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20807
NP_000061.1
821
94254
S474
E
D
D
D
P
D
D
S
E
V
I
C
S
F
L
Chimpanzee
Pan troglodytes
XP_510336
796
91174
I458
L
F
T
I
G
F
A
I
Y
E
V
P
K
E
M
Rhesus Macaque
Macaca mulatta
XP_001103220
821
94279
S474
E
D
D
D
P
D
D
S
E
V
I
C
S
F
L
Dog
Lupus familis
XP_849420
821
94311
S474
E
D
D
D
P
D
D
S
E
V
I
C
S
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q64691
821
94195
S474
E
D
D
D
P
E
D
S
E
V
I
C
S
F
L
Rat
Rattus norvegicus
P16259
821
94109
S474
E
D
D
D
P
D
D
S
E
V
I
C
S
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92177
810
93542
E467
E
D
D
D
P
E
D
E
E
V
I
C
S
F
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001004571
725
83878
I438
L
G
A
N
L
L
T
I
G
F
S
I
Y
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VT65
925
103795
E615
S
L
E
D
P
D
D
E
D
D
D
G
K
C
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.9
97.9
92.8
N.A.
93.5
94
N.A.
N.A.
77.7
N.A.
58.2
N.A.
29.8
N.A.
N.A.
N.A.
Protein Similarity:
100
93.1
99
96.8
N.A.
97.1
97
N.A.
N.A.
87.5
N.A.
69
N.A.
47.4
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
93.3
100
N.A.
N.A.
86.6
N.A.
0
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
13.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
67
0
12
0
% C
% Asp:
0
67
67
78
0
56
78
0
12
12
12
0
0
0
0
% D
% Glu:
67
0
12
0
0
23
0
23
67
12
0
0
0
23
0
% E
% Phe:
0
12
0
0
0
12
0
0
0
12
0
0
0
67
0
% F
% Gly:
0
12
0
0
12
0
0
0
12
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
0
23
0
0
67
12
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% K
% Leu:
23
12
0
0
12
12
0
0
0
0
0
0
0
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
78
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
0
0
0
56
0
0
12
0
67
0
0
% S
% Thr:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
12
% T
% Val:
0
0
0
0
0
0
0
0
0
67
12
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _