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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAST
All Species:
10.61
Human Site:
S549
Identified Species:
25.93
UniProt:
P20810
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20810
NP_775086.1
708
76573
S549
V
V
S
Q
T
P
A
S
T
T
Q
A
G
A
P
Chimpanzee
Pan troglodytes
XP_518168
988
106575
S829
V
V
S
Q
T
P
A
S
T
T
Q
A
G
A
P
Rhesus Macaque
Macaca mulatta
XP_001091928
847
91183
S683
V
V
S
Q
T
P
A
S
T
T
H
T
G
A
P
Dog
Lupus familis
XP_848621
747
79896
P583
V
V
S
Q
T
P
A
P
T
T
H
S
A
G
L
Cat
Felis silvestris
Mouse
Mus musculus
P51125
788
84903
P627
V
V
S
Q
T
P
A
P
S
T
H
A
A
A
P
Rat
Rattus norvegicus
P27321
713
77294
P554
T
V
S
Q
V
P
A
P
S
N
H
T
A
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512320
853
89249
E669
H
E
D
G
S
R
A
E
S
S
S
A
P
F
C
Chicken
Gallus gallus
NP_001131122
768
81427
I601
D
V
I
S
A
S
T
I
S
S
V
H
S
A
A
Frog
Xenopus laevis
NP_001081910
931
96808
A766
D
V
V
S
C
S
K
A
S
A
V
K
S
G
A
Zebra Danio
Brachydanio rerio
NP_001124063
818
85259
S622
V
A
S
S
S
A
S
S
V
H
S
A
V
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.7
79
69.7
N.A.
61
64
N.A.
49.4
44
32.8
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
67.8
79.9
78
N.A.
70.8
74.7
N.A.
60.9
60
44.6
40.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
60
N.A.
73.3
46.6
N.A.
13.3
13.3
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
66.6
N.A.
80
53.3
N.A.
33.3
26.6
20
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
10
70
10
0
10
0
50
30
60
20
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
20
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
30
20
10
% G
% His:
10
0
0
0
0
0
0
0
0
10
40
10
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
60
0
30
0
0
0
0
10
0
50
% P
% Gln:
0
0
0
60
0
0
0
0
0
0
20
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
70
30
20
20
10
40
50
20
20
10
20
10
0
% S
% Thr:
10
0
0
0
50
0
10
0
40
50
0
20
0
0
0
% T
% Val:
60
80
10
0
10
0
0
0
10
0
20
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _