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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP2B6
All Species:
13.94
Human Site:
Y484
Identified Species:
61.33
UniProt:
P20813
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20813
NP_000758.1
491
56278
Y484
V
G
K
I
P
P
T
Y
Q
I
R
F
L
P
R
Chimpanzee
Pan troglodytes
XP_001139878
477
54577
Rhesus Macaque
Macaca mulatta
NP_001035302
491
55943
Y484
V
G
K
I
P
P
T
Y
Q
I
R
F
L
P
R
Dog
Lupus familis
XP_855605
494
56234
Y484
V
G
K
L
P
P
V
Y
Q
I
S
F
L
S
R
Cat
Felis silvestris
Mouse
Mus musculus
O55071
492
55978
Y485
A
T
K
T
P
P
Q
Y
Q
I
H
F
L
S
R
Rat
Rattus norvegicus
Q64583
495
56302
Y485
I
S
K
I
P
S
P
Y
Q
I
H
F
L
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.9
91.4
77.5
N.A.
74.8
71.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
75.9
95.7
87
N.A.
85.1
84
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
73.3
N.A.
60
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
100
80
N.A.
60
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
84
0
0
0
% F
% Gly:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% H
% Ile:
17
0
0
50
0
0
0
0
0
84
0
0
0
0
0
% I
% Lys:
0
0
84
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
17
0
0
0
0
0
0
0
0
84
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
84
67
17
0
0
0
0
0
0
34
0
% P
% Gln:
0
0
0
0
0
0
17
0
84
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
84
% R
% Ser:
0
17
0
0
0
17
0
0
0
0
17
0
0
50
0
% S
% Thr:
0
17
0
17
0
0
34
0
0
0
0
0
0
0
0
% T
% Val:
50
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _