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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFNA1
All Species:
14.55
Human Site:
T22
Identified Species:
32
UniProt:
P20827
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20827
NP_004419.2
205
23787
T22
L
A
A
A
D
R
H
T
V
F
W
N
S
S
N
Chimpanzee
Pan troglodytes
XP_001141980
333
38071
T22
L
V
S
A
D
R
H
T
V
F
W
N
S
S
N
Rhesus Macaque
Macaca mulatta
XP_001115135
205
23806
T22
L
A
A
A
D
R
H
T
V
F
W
N
S
S
N
Dog
Lupus familis
XP_852071
205
23822
T22
L
A
A
A
D
R
H
T
V
F
W
N
S
S
N
Cat
Felis silvestris
Mouse
Mus musculus
P52793
205
23784
I22
L
A
A
A
D
R
H
I
V
F
W
N
S
S
N
Rat
Rattus norvegicus
P97553
205
23745
I22
L
A
A
A
D
R
H
I
V
F
W
N
S
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516025
177
20198
Chicken
Gallus gallus
P52804
228
26187
Y32
R
K
A
V
A
D
R
Y
A
V
Y
W
N
S
T
Frog
Xenopus laevis
P52794
216
24737
I32
E
A
Q
G
E
R
H
I
V
F
W
N
S
S
N
Zebra Danio
Brachydanio rerio
P79727
195
22669
R21
V
S
V
W
S
D
D
R
I
I
S
D
R
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O44516
348
39575
I24
L
A
A
A
D
E
H
I
V
Y
W
N
S
T
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.4
97.5
89.7
N.A.
85.8
86.3
N.A.
57.5
41.6
53.7
41.9
N.A.
N.A.
N.A.
21.2
N.A.
Protein Similarity:
100
60.3
99
95.1
N.A.
92.1
92.6
N.A.
71.2
54.3
68.9
59
N.A.
N.A.
N.A.
34.7
N.A.
P-Site Identity:
100
86.6
100
100
N.A.
93.3
93.3
N.A.
0
13.3
66.6
0
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
93.3
93.3
N.A.
0
26.6
73.3
26.6
N.A.
N.A.
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
64
64
64
10
0
0
0
10
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
64
19
10
0
0
0
0
10
0
0
0
% D
% Glu:
10
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
73
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
37
10
10
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
64
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
73
10
0
73
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
64
10
10
0
0
0
0
10
0
0
% R
% Ser:
0
10
10
0
10
0
0
0
0
0
10
0
73
73
0
% S
% Thr:
0
0
0
0
0
0
0
37
0
0
0
0
0
10
10
% T
% Val:
10
10
10
10
0
0
0
0
73
10
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
73
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _