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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINA2
All Species:
23.94
Human Site:
S345
Identified Species:
65.83
UniProt:
P20848
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20848
NP_000286
420
47891
S345
F
S
N
E
A
D
L
S
G
V
S
Q
E
A
P
Chimpanzee
Pan troglodytes
XP_522938
418
46674
S343
F
S
N
G
A
D
L
S
G
V
T
E
E
A
P
Rhesus Macaque
Macaca mulatta
XP_001098235
419
47544
S344
F
S
N
E
A
D
L
S
G
A
S
Q
E
A
P
Dog
Lupus familis
XP_547961
294
34152
E220
S
A
E
A
D
L
S
E
I
T
E
E
G
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q00897
413
45980
G338
N
N
G
A
D
L
S
G
I
T
E
E
N
A
P
Rat
Rattus norvegicus
P17475
411
46117
S337
F
N
N
D
A
D
L
S
G
I
T
E
D
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518875
498
56680
S348
F
T
E
E
A
D
F
S
G
I
T
E
Q
S
R
Chicken
Gallus gallus
XP_421342
425
47718
S344
F
T
N
Q
A
D
L
S
G
I
S
G
V
P
E
Frog
Xenopus laevis
NP_001081358
433
48891
T359
F
S
D
E
A
D
L
T
G
I
V
E
E
A
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.2
88.5
34.5
N.A.
50.9
53.3
N.A.
32.9
38.5
39.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73.3
93.5
46.4
N.A.
65
68.3
N.A.
50.5
57.1
58.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
80
93.3
0
N.A.
13.3
60
N.A.
40
53.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
13.3
N.A.
26.6
100
N.A.
80
73.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
23
78
0
0
0
0
12
0
0
0
67
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
12
23
78
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
0
23
45
0
0
0
12
0
0
23
67
45
0
12
% E
% Phe:
78
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
12
0
0
0
12
78
0
0
12
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
23
45
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
0
0
0
0
0
23
67
0
0
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
23
56
0
0
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
56
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
23
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
12
45
0
0
0
0
23
67
0
0
34
0
0
12
0
% S
% Thr:
0
23
0
0
0
0
0
12
0
23
34
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
23
12
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _