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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP2A7
All Species:
22.12
Human Site:
S224
Identified Species:
69.52
UniProt:
P20853
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20853
NP_000755.2
494
56425
S224
G
Q
L
Y
E
M
F
S
S
V
M
K
H
L
P
Chimpanzee
Pan troglodytes
XP_001139878
477
54577
S229
G
Q
L
Y
E
M
F
S
S
V
M
K
H
L
P
Rhesus Macaque
Macaca mulatta
NP_001035305
494
56567
S224
G
Q
L
Y
E
M
F
S
S
V
M
K
H
L
P
Dog
Lupus familis
XP_541606
494
56439
S224
A
Q
L
Y
D
M
Y
S
G
I
M
Q
Y
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P20852
494
56722
S224
G
Q
L
Y
E
M
F
S
S
V
M
K
H
L
P
Rat
Rattus norvegicus
P20812
494
56492
S224
G
Q
L
Y
E
M
F
S
S
V
M
K
H
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P20678
491
56467
P223
T
Q
L
Y
N
F
F
P
T
I
L
D
Y
L
P
Frog
Xenopus laevis
NP_001085249
495
57473
P224
G
Q
L
M
T
M
L
P
I
I
M
K
H
I
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.6
93.1
58.9
N.A.
83.4
84.6
N.A.
N.A.
52.4
53.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
79.1
95.9
77.1
N.A.
91.9
91.6
N.A.
N.A.
71.4
71.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
53.3
N.A.
100
100
N.A.
N.A.
40
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
N.A.
66.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
13
0
0
0
0
0
0
13
0
0
0
% D
% Glu:
0
0
0
0
63
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
13
75
0
0
0
0
0
0
0
0
% F
% Gly:
75
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
75
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
13
38
0
0
0
13
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% K
% Leu:
0
0
100
0
0
0
13
0
0
0
13
0
0
88
0
% L
% Met:
0
0
0
13
0
88
0
0
0
0
88
0
0
0
0
% M
% Asn:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
100
% P
% Gln:
0
100
0
0
0
0
0
0
0
0
0
13
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
75
63
0
0
0
0
0
0
% S
% Thr:
13
0
0
0
13
0
0
0
13
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
63
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
88
0
0
13
0
0
0
0
0
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _