Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP2A7 All Species: 24.85
Human Site: T258 Identified Species: 78.1
UniProt: P20853 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20853 NP_000755.2 494 56425 T258 K V E H N Q R T L D P N S P Q
Chimpanzee Pan troglodytes XP_001139878 477 54577 T263 K V E H N Q R T L D P N S P R
Rhesus Macaque Macaca mulatta NP_001035305 494 56567 T258 K V E H N Q H T L D P N S P R
Dog Lupus familis XP_541606 494 56439 S258 R V K I N E A S L D P Q N P R
Cat Felis silvestris
Mouse Mus musculus P20852 494 56722 T258 K V E H N Q R T L D P N S P R
Rat Rattus norvegicus P20812 494 56492 T258 K V E Q N Q R T L D P N S P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P20678 491 56467 Q255 T E I I R A H Q E S F D A S C
Frog Xenopus laevis NP_001085249 495 57473 T258 R V N E N E K T L D P K S P R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.6 93.1 58.9 N.A. 83.4 84.6 N.A. N.A. 52.4 53.7 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 79.1 95.9 77.1 N.A. 91.9 91.6 N.A. N.A. 71.4 71.9 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 86.6 40 N.A. 93.3 86.6 N.A. N.A. 0 53.3 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 80 N.A. 100 93.3 N.A. N.A. 13.3 80 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 13 13 0 0 0 0 0 13 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % C
% Asp: 0 0 0 0 0 0 0 0 0 88 0 13 0 0 0 % D
% Glu: 0 13 63 13 0 25 0 0 13 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 50 0 0 25 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 13 25 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 63 0 13 0 0 0 13 0 0 0 0 13 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 88 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 13 0 88 0 0 0 0 0 0 63 13 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 88 0 0 88 0 % P
% Gln: 0 0 0 13 0 63 0 13 0 0 0 13 0 0 13 % Q
% Arg: 25 0 0 0 13 0 50 0 0 0 0 0 0 0 75 % R
% Ser: 0 0 0 0 0 0 0 13 0 13 0 0 75 13 0 % S
% Thr: 13 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % T
% Val: 0 88 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _