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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGA All Species: 16.06
Human Site: S327 Identified Species: 27.18
UniProt: P20933 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20933 NP_000018.1 346 37208 S327 L S T F T Q F S F M V Y N S E
Chimpanzee Pan troglodytes XP_517545 346 37219 S327 L S T F T Q F S F M V Y N S E
Rhesus Macaque Macaca mulatta XP_001090811 283 30196 R265 G D G D I L M R F L P R Y H F
Dog Lupus familis XP_532851 343 36656 S324 L P T F T Q F S F M V Y N S L
Cat Felis silvestris
Mouse Mus musculus Q64191 346 37003 S327 L P T F T Q F S F M V S N S L
Rat Rattus norvegicus P30919 345 37149 S326 L P T F T Q F S F M V Y N S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517749 485 52220 R466 L P E F S Q F R F M V Y H S L
Chicken Gallus gallus NP_001006445 345 36612 H326 I P G F T Q F H F M V F S P L
Frog Xenopus laevis Q6GM78 309 32487 L291 A A V K D D Q L H I G I Y H G
Zebra Danio Brachydanio rerio Q5BKW9 310 32910 L292 A A A Q Q G K L H F G L F H G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MR45 393 42222 V364 L A E F P F M V S S P A G A D
Honey Bee Apis mellifera XP_394866 358 39226 V330 I T R F A Y Y V A N P E L E K
Nematode Worm Caenorhab. elegans Q21697 363 39340 V332 I N K F G Y N V A F Q N G T V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q56W64 359 38231 Q341 A C Y G W T F Q Y S V Q N P D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 74.8 83.2 N.A. 82.3 82 N.A. 50.7 65 30.9 28.6 N.A. 48 50.5 46 N.A.
Protein Similarity: 100 99.7 79.1 90.1 N.A. 88.1 88.1 N.A. 58.9 76 48.2 47.4 N.A. 61.8 62.2 61.4 N.A.
P-Site Identity: 100 100 6.6 86.6 N.A. 80 86.6 N.A. 60 46.6 0 0 N.A. 13.3 6.6 6.6 N.A.
P-Site Similarity: 100 100 13.3 86.6 N.A. 80 86.6 N.A. 73.3 66.6 13.3 6.6 N.A. 33.3 33.3 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 47.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 61.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 22 8 0 8 0 0 0 15 0 0 8 0 8 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 8 8 0 0 0 0 0 0 0 0 15 % D
% Glu: 0 0 15 0 0 0 0 0 0 0 0 8 0 8 15 % E
% Phe: 0 0 0 72 0 8 58 0 58 15 0 8 8 0 8 % F
% Gly: 8 0 15 8 8 8 0 0 0 0 15 0 15 0 15 % G
% His: 0 0 0 0 0 0 0 8 15 0 0 0 8 22 0 % H
% Ile: 22 0 0 0 8 0 0 0 0 8 0 8 0 0 0 % I
% Lys: 0 0 8 8 0 0 8 0 0 0 0 0 0 0 8 % K
% Leu: 50 0 0 0 0 8 0 15 0 8 0 8 8 0 36 % L
% Met: 0 0 0 0 0 0 15 0 0 50 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 8 0 0 8 0 8 43 0 0 % N
% Pro: 0 36 0 0 8 0 0 0 0 0 22 0 0 15 0 % P
% Gln: 0 0 0 8 8 50 8 8 0 0 8 8 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 15 0 0 0 8 0 0 0 % R
% Ser: 0 15 0 0 8 0 0 36 8 15 0 8 8 43 0 % S
% Thr: 0 8 36 0 43 8 0 0 0 0 0 0 0 8 0 % T
% Val: 0 0 8 0 0 0 0 22 0 0 58 0 0 0 8 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 15 8 0 8 0 0 36 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _