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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGA All Species: 30.91
Human Site: Y270 Identified Species: 52.31
UniProt: P20933 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20933 NP_000018.1 346 37208 Y270 L M R F L P S Y Q A V E Y M R
Chimpanzee Pan troglodytes XP_517545 346 37219 Y270 L M R F L P S Y Q A V E Y M R
Rhesus Macaque Macaca mulatta XP_001090811 283 30196 I212 D T I G M V V I H K T G R I A
Dog Lupus familis XP_532851 343 36656 Y267 L M R F L P S Y Q A V E Y M R
Cat Felis silvestris
Mouse Mus musculus Q64191 346 37003 Y270 L L R F L P S Y Q A V E Y M R
Rat Rattus norvegicus P30919 345 37149 Y269 L L R F L P S Y Q A V E Y M R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517749 485 52220 Y409 M M R F L P S Y Q A V E Y M R
Chicken Gallus gallus NP_001006445 345 36612 Y269 M M R F L P S Y Q A V E Y M R
Frog Xenopus laevis Q6GM78 309 32487 Q238 L I L H H M E Q G K S P E E A
Zebra Danio Brachydanio rerio Q5BKW9 310 32910 Q239 L V L F H M E Q G K T P E E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MR45 393 42222 L307 M M R F L P S L L A V E T M R
Honey Bee Apis mellifera XP_394866 358 39226 F273 M M R F L P S F L A V E E M R
Nematode Worm Caenorhab. elegans Q21697 363 39340 F276 M R F L P S F F A V T Q M E L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q56W64 359 38231 Y288 M M R F L P C Y Q V V E S M R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 74.8 83.2 N.A. 82.3 82 N.A. 50.7 65 30.9 28.6 N.A. 48 50.5 46 N.A.
Protein Similarity: 100 99.7 79.1 90.1 N.A. 88.1 88.1 N.A. 58.9 76 48.2 47.4 N.A. 61.8 62.2 61.4 N.A.
P-Site Identity: 100 100 0 100 N.A. 93.3 93.3 N.A. 93.3 93.3 6.6 13.3 N.A. 73.3 73.3 0 N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 100 100 13.3 20 N.A. 80 86.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 47.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 61.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 73.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 80 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 65 0 0 0 0 22 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 15 0 0 0 0 72 22 22 0 % E
% Phe: 0 0 8 79 0 0 8 15 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 15 0 0 8 0 0 0 % G
% His: 0 0 0 8 15 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 0 0 8 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 22 0 0 0 0 0 % K
% Leu: 50 15 15 8 72 0 0 8 15 0 0 0 0 0 8 % L
% Met: 43 58 0 0 8 15 0 0 0 0 0 0 8 72 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 8 72 0 0 0 0 0 15 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 15 58 0 0 8 0 0 0 % Q
% Arg: 0 8 72 0 0 0 0 0 0 0 0 0 8 0 72 % R
% Ser: 0 0 0 0 0 8 65 0 0 0 8 0 8 0 0 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 22 0 8 0 0 % T
% Val: 0 8 0 0 0 8 8 0 0 15 72 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 58 0 0 0 0 50 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _