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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGA All Species: 31.82
Human Site: Y275 Identified Species: 53.85
UniProt: P20933 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20933 NP_000018.1 346 37208 Y275 P S Y Q A V E Y M R R G E D P
Chimpanzee Pan troglodytes XP_517545 346 37219 Y275 P S Y Q A V E Y M R R G E D P
Rhesus Macaque Macaca mulatta XP_001090811 283 30196 R217 V V I H K T G R I A A G T S T
Dog Lupus familis XP_532851 343 36656 Y272 P S Y Q A V E Y M R Q G E D P
Cat Felis silvestris
Mouse Mus musculus Q64191 346 37003 Y275 P S Y Q A V E Y M R G G D D P
Rat Rattus norvegicus P30919 345 37149 Y274 P S Y Q A V E Y M R G G D D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517749 485 52220 Y414 P S Y Q A V E Y M R A G D D P
Chicken Gallus gallus NP_001006445 345 36612 Y274 P S Y Q A V E Y M R M G T D P
Frog Xenopus laevis Q6GM78 309 32487 E243 M E Q G K S P E E A A D A G L
Zebra Danio Brachydanio rerio Q5BKW9 310 32910 E244 M E Q G K T P E E A S D L A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MR45 393 42222 T312 P S L L A V E T M R A G K P P
Honey Bee Apis mellifera XP_394866 358 39226 E278 P S F L A V E E M R R N A T P
Nematode Worm Caenorhab. elegans Q21697 363 39340 M281 S F F A V T Q M E L G T K P S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q56W64 359 38231 S293 P C Y Q V V E S M R Q G M K P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 74.8 83.2 N.A. 82.3 82 N.A. 50.7 65 30.9 28.6 N.A. 48 50.5 46 N.A.
Protein Similarity: 100 99.7 79.1 90.1 N.A. 88.1 88.1 N.A. 58.9 76 48.2 47.4 N.A. 61.8 62.2 61.4 N.A.
P-Site Identity: 100 100 6.6 93.3 N.A. 86.6 86.6 N.A. 86.6 86.6 0 0 N.A. 60 60 0 N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 93.3 N.A. 93.3 86.6 0 0 N.A. 66.6 66.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 47.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 61.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 60 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 65 0 0 0 0 22 29 0 15 8 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 15 22 50 0 % D
% Glu: 0 15 0 0 0 0 72 22 22 0 0 0 22 0 0 % E
% Phe: 0 8 15 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 15 0 0 8 0 0 0 22 72 0 8 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 22 0 0 0 0 0 0 0 15 8 0 % K
% Leu: 0 0 8 15 0 0 0 0 0 8 0 0 8 0 15 % L
% Met: 15 0 0 0 0 0 0 8 72 0 8 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 72 0 0 0 0 0 15 0 0 0 0 0 0 15 72 % P
% Gln: 0 0 15 58 0 0 8 0 0 0 15 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 72 22 0 0 0 0 % R
% Ser: 8 65 0 0 0 8 0 8 0 0 8 0 0 8 8 % S
% Thr: 0 0 0 0 0 22 0 8 0 0 0 8 15 8 8 % T
% Val: 8 8 0 0 15 72 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 58 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _