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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGA All Species: 20
Human Site: Y331 Identified Species: 33.85
UniProt: P20933 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20933 NP_000018.1 346 37208 Y331 T Q F S F M V Y N S E K N Q P
Chimpanzee Pan troglodytes XP_517545 346 37219 Y331 T Q F S F M V Y N S E K N Q P
Rhesus Macaque Macaca mulatta XP_001090811 283 30196 R269 I L M R F L P R Y H F L V Y I
Dog Lupus familis XP_532851 343 36656 Y328 T Q F S F M V Y N S L R N Q P
Cat Felis silvestris
Mouse Mus musculus Q64191 346 37003 S331 T Q F S F M V S N S L H N E P
Rat Rattus norvegicus P30919 345 37149 Y330 T Q F S F M V Y N S L H N Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517749 485 52220 Y470 S Q F R F M V Y H S L Q S Q P
Chicken Gallus gallus NP_001006445 345 36612 F330 T Q F H F M V F S P L Q S Q P
Frog Xenopus laevis Q6GM78 309 32487 I295 D D Q L H I G I Y H G E N N V
Zebra Danio Brachydanio rerio Q5BKW9 310 32910 L296 Q G K L H F G L F H G D H F T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MR45 393 42222 A368 P F M V S S P A G A D G P T R
Honey Bee Apis mellifera XP_394866 358 39226 E334 A Y Y V A N P E L E K P T I H
Nematode Worm Caenorhab. elegans Q21697 363 39340 N336 G Y N V A F Q N G T V V T Y S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q56W64 359 38231 Q345 W T F Q Y S V Q N P D M N D V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 74.8 83.2 N.A. 82.3 82 N.A. 50.7 65 30.9 28.6 N.A. 48 50.5 46 N.A.
Protein Similarity: 100 99.7 79.1 90.1 N.A. 88.1 88.1 N.A. 58.9 76 48.2 47.4 N.A. 61.8 62.2 61.4 N.A.
P-Site Identity: 100 100 6.6 86.6 N.A. 73.3 80 N.A. 60 53.3 6.6 0 N.A. 0 0 0 N.A.
P-Site Similarity: 100 100 13.3 93.3 N.A. 80 80 N.A. 86.6 80 20 6.6 N.A. 13.3 13.3 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 47.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 61.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 15 0 0 8 0 8 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 0 0 0 0 0 15 8 0 8 0 % D
% Glu: 0 0 0 0 0 0 0 8 0 8 15 8 0 8 0 % E
% Phe: 0 8 58 0 58 15 0 8 8 0 8 0 0 8 0 % F
% Gly: 8 8 0 0 0 0 15 0 15 0 15 8 0 0 0 % G
% His: 0 0 0 8 15 0 0 0 8 22 0 15 8 0 8 % H
% Ile: 8 0 0 0 0 8 0 8 0 0 0 0 0 8 8 % I
% Lys: 0 0 8 0 0 0 0 0 0 0 8 15 0 0 0 % K
% Leu: 0 8 0 15 0 8 0 8 8 0 36 8 0 0 0 % L
% Met: 0 0 15 0 0 50 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 8 0 0 8 0 8 43 0 0 0 50 8 0 % N
% Pro: 8 0 0 0 0 0 22 0 0 15 0 8 8 0 43 % P
% Gln: 8 50 8 8 0 0 8 8 0 0 0 15 0 43 0 % Q
% Arg: 0 0 0 15 0 0 0 8 0 0 0 8 0 0 8 % R
% Ser: 8 0 0 36 8 15 0 8 8 43 0 0 15 0 8 % S
% Thr: 43 8 0 0 0 0 0 0 0 8 0 0 15 8 8 % T
% Val: 0 0 0 22 0 0 58 0 0 0 8 8 8 0 15 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 15 8 0 8 0 0 36 15 0 0 0 0 15 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _