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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDC All Species: 16.97
Human Site: S45 Identified Species: 33.94
UniProt: P20941 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20941 NP_002588.3 246 28246 S45 D S D S I P P S K K E I L R Q
Chimpanzee Pan troglodytes XP_524997 413 46384 S212 D S D S I P P S K K E I L R Q
Rhesus Macaque Macaca mulatta XP_001107723 274 31485 S73 D S D S I P P S K K E I L R Q
Dog Lupus familis XP_852231 301 34185 S92 E R L V K K L S M T C R S H L
Cat Felis silvestris
Mouse Mus musculus Q9QW08 244 27998 P44 E D G D S I P P S K K E I L R
Rat Rattus norvegicus P20942 246 28111 S45 D G D S I P P S K K E I L R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516854 245 28140 S44 E D S D S V P S K K E I L R Q
Chicken Gallus gallus XP_426634 247 28345 E46 S L P L S K K E I L R Q M S S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_682823 236 27114 P38 S E D H E S I P S N K R E L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUR7 276 30957 K73 T G P K G V V K D W Q R F K Q
Honey Bee Apis mellifera XP_393706 284 32413 K69 T G P K G V I K D W Q R Y K Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799253 293 33509 K78 L A D W R R F K Q L E T E K R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59 87.9 40.5 N.A. 88.2 87.8 N.A. 73.5 72 N.A. 61.7 N.A. 28.9 30.2 N.A. 30
Protein Similarity: 100 59.3 89 61.4 N.A. 95.1 94.7 N.A. 86.5 85 N.A. 79.2 N.A. 50 50.3 N.A. 50.1
P-Site Identity: 100 100 100 6.6 N.A. 13.3 93.3 N.A. 60 0 N.A. 6.6 N.A. 6.6 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 13.3 N.A. 40 93.3 N.A. 66.6 6.6 N.A. 13.3 N.A. 20 20 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 34 17 50 17 0 0 0 0 17 0 0 0 0 0 0 % D
% Glu: 25 9 0 0 9 0 0 9 0 0 50 9 17 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 0 % F
% Gly: 0 25 9 0 17 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 34 9 17 0 9 0 0 42 9 0 0 % I
% Lys: 0 0 0 17 9 17 9 25 42 50 17 0 0 25 0 % K
% Leu: 9 9 9 9 0 0 9 0 0 17 0 0 42 17 17 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % N
% Pro: 0 0 25 0 0 34 50 17 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 9 0 17 9 0 0 59 % Q
% Arg: 0 9 0 0 9 9 0 0 0 0 9 34 0 42 17 % R
% Ser: 17 25 9 34 25 9 0 50 17 0 0 0 9 9 9 % S
% Thr: 17 0 0 0 0 0 0 0 0 9 0 9 0 0 0 % T
% Val: 0 0 0 9 0 25 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 9 0 0 0 0 0 17 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _