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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDC All Species: 16.97
Human Site: S54 Identified Species: 33.94
UniProt: P20941 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20941 NP_002588.3 246 28246 S54 K E I L R Q M S S P Q S R N G
Chimpanzee Pan troglodytes XP_524997 413 46384 S221 K E I L R Q M S S P Q S R N G
Rhesus Macaque Macaca mulatta XP_001107723 274 31485 S82 K E I L R Q M S S P Q S R N G
Dog Lupus familis XP_852231 301 34185 E101 T C R S H L D E E E D Q H R Q
Cat Felis silvestris
Mouse Mus musculus Q9QW08 244 27998 M53 K K E I L R Q M S S P Q S R D
Rat Rattus norvegicus P20942 246 28111 S54 K E I L R Q M S S P Q S R D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516854 245 28140 S53 K E I L R Q L S S P H R R D N
Chicken Gallus gallus XP_426634 247 28345 H55 L R Q M S S P H R S F S K D D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_682823 236 27114 Q47 N K R E L L R Q M S N P K S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUR7 276 30957 E82 W Q R F K Q L E A E R R D E T
Honey Bee Apis mellifera XP_393706 284 32413 Q78 W Q R Y K Q L Q A E K R D E Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799253 293 33509 D87 L E T E K R G D Q D R E K R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59 87.9 40.5 N.A. 88.2 87.8 N.A. 73.5 72 N.A. 61.7 N.A. 28.9 30.2 N.A. 30
Protein Similarity: 100 59.3 89 61.4 N.A. 95.1 94.7 N.A. 86.5 85 N.A. 79.2 N.A. 50 50.3 N.A. 50.1
P-Site Identity: 100 100 100 0 N.A. 13.3 86.6 N.A. 66.6 6.6 N.A. 0 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 0 N.A. 33.3 93.3 N.A. 80 26.6 N.A. 20 N.A. 40 40 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 9 9 0 9 9 0 17 25 25 % D
% Glu: 0 50 9 17 0 0 0 17 9 25 0 9 0 17 0 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 25 % G
% His: 0 0 0 0 9 0 0 9 0 0 9 0 9 0 0 % H
% Ile: 0 0 42 9 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 50 17 0 0 25 0 0 0 0 0 9 0 25 0 0 % K
% Leu: 17 0 0 42 17 17 25 0 0 0 0 0 0 0 9 % L
% Met: 0 0 0 9 0 0 34 9 9 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 9 0 0 25 9 % N
% Pro: 0 0 0 0 0 0 9 0 0 42 9 9 0 0 0 % P
% Gln: 0 17 9 0 0 59 9 17 9 0 34 17 0 0 17 % Q
% Arg: 0 9 34 0 42 17 9 0 9 0 17 25 42 25 0 % R
% Ser: 0 0 0 9 9 9 0 42 50 25 0 42 9 9 9 % S
% Thr: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _