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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDC All Species: 28.48
Human Site: Y77 Identified Species: 56.97
UniProt: P20941 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20941 NP_002588.3 246 28246 Y77 R K M S I Q E Y E L I H K E K
Chimpanzee Pan troglodytes XP_524997 413 46384 Y244 R K M S I Q E Y E L I H K E K
Rhesus Macaque Macaca mulatta XP_001107723 274 31485 Y105 R K M S I Q E Y E L I H K E K
Dog Lupus familis XP_852231 301 34185 F124 G K M T L K E F A V M N E D Q
Cat Felis silvestris
Mouse Mus musculus Q9QW08 244 27998 E76 K M S I Q E Y E L I H Q D K E
Rat Rattus norvegicus P20942 246 28111 Y77 R K M S I Q E Y E L I H Q D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516854 245 28140 Y76 R K M S V Q E Y E L I H Q E K
Chicken Gallus gallus XP_426634 247 28345 Y78 R K M S M Q E Y E L I N D E K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_682823 236 27114 Y70 R K M S V Q E Y E M I Q E E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUR7 276 30957 T105 K K L T I T A T T S A E D E E
Honey Bee Apis mellifera XP_393706 284 32413 R101 K K L S L T C R S S L D E E K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799253 293 33509 E110 C R S Y L D D E K A K E D E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59 87.9 40.5 N.A. 88.2 87.8 N.A. 73.5 72 N.A. 61.7 N.A. 28.9 30.2 N.A. 30
Protein Similarity: 100 59.3 89 61.4 N.A. 95.1 94.7 N.A. 86.5 85 N.A. 79.2 N.A. 50 50.3 N.A. 50.1
P-Site Identity: 100 100 100 20 N.A. 0 86.6 N.A. 86.6 80 N.A. 66.6 N.A. 20 26.6 N.A. 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 33.3 100 N.A. 100 93.3 N.A. 86.6 N.A. 46.6 60 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 9 9 9 0 0 0 0 % A
% Cys: 9 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 9 0 0 0 0 9 34 17 9 % D
% Glu: 0 0 0 0 0 9 67 17 59 0 0 17 25 75 25 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 42 0 0 0 % H
% Ile: 0 0 0 9 42 0 0 0 0 9 59 0 0 0 0 % I
% Lys: 25 84 0 0 0 9 0 0 9 0 9 0 25 9 59 % K
% Leu: 0 0 17 0 25 0 0 0 9 50 9 0 0 0 0 % L
% Met: 0 9 67 0 9 0 0 0 0 9 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 9 59 0 0 0 0 0 17 17 0 9 % Q
% Arg: 59 9 0 0 0 0 0 9 0 0 0 0 0 0 0 % R
% Ser: 0 0 17 67 0 0 0 0 9 17 0 0 0 0 0 % S
% Thr: 0 0 0 17 0 17 0 9 9 0 0 0 0 0 0 % T
% Val: 0 0 0 0 17 0 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 9 59 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _