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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPS1L1
All Species:
40.91
Human Site:
S108
Identified Species:
81.82
UniProt:
P21108
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21108
NP_787082.1
318
34839
S108
D
K
S
R
S
P
I
S
A
K
L
V
A
N
M
Chimpanzee
Pan troglodytes
XP_528013
318
34770
S108
D
K
S
R
A
P
I
S
A
K
L
V
A
N
M
Rhesus Macaque
Macaca mulatta
XP_001105054
318
34745
S108
D
K
S
R
A
P
I
S
A
K
L
V
A
N
M
Dog
Lupus familis
XP_862484
326
35836
K108
D
K
K
C
F
L
T
K
W
I
S
R
A
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7G0
318
34830
S108
D
K
S
R
A
P
I
S
A
K
L
V
A
N
M
Rat
Rattus norvegicus
P60892
318
34816
S108
D
K
S
R
A
P
I
S
A
K
L
V
A
N
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI49
325
35645
R108
D
K
K
G
A
V
E
R
W
S
R
A
P
I
S
Frog
Xenopus laevis
Q7ZXC9
318
34683
S108
D
K
S
R
A
P
I
S
A
K
L
V
A
N
M
Zebra Danio
Brachydanio rerio
NP_001070036
318
34782
S108
D
K
S
R
A
P
I
S
A
K
L
V
A
N
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648345
350
38261
S140
D
K
S
R
A
P
I
S
A
K
L
V
A
N
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790052
315
34329
S108
D
K
S
R
A
P
I
S
A
K
L
V
A
N
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38063
327
35828
T120
D
K
S
R
A
P
I
T
A
K
L
V
A
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
97.1
92
N.A.
94
94.3
N.A.
N.A.
88.3
91.1
93
N.A.
78
N.A.
N.A.
85.2
Protein Similarity:
100
99
98.7
94.7
N.A.
97.1
97.1
N.A.
N.A.
93.5
95.9
97.1
N.A.
84.5
N.A.
N.A.
92.1
P-Site Identity:
100
93.3
93.3
20
N.A.
93.3
93.3
N.A.
N.A.
13.3
93.3
93.3
N.A.
93.3
N.A.
N.A.
93.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
N.A.
20
100
100
N.A.
100
N.A.
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
60.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
76.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
84
0
0
0
84
0
0
9
92
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
84
0
0
9
0
0
0
9
9
% I
% Lys:
0
100
17
0
0
0
0
9
0
84
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
0
0
0
0
84
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
84
0
% N
% Pro:
0
0
0
0
0
84
0
0
0
0
0
0
9
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
84
0
0
0
9
0
0
9
9
0
0
0
% R
% Ser:
0
0
84
0
9
0
0
75
0
9
9
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
84
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _