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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRPS1L1 All Species: 49.39
Human Site: S310 Identified Species: 98.79
UniProt: P21108 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P21108 NP_787082.1 318 34839 S310 T H N G E S V S Y L F S H V P
Chimpanzee Pan troglodytes XP_528013 318 34770 S310 T H N G E S V S Y L F S H V P
Rhesus Macaque Macaca mulatta XP_001105054 318 34745 S310 T H N G E S V S Y L F S H V P
Dog Lupus familis XP_862484 326 35836 S318 T H N G E S V S Y L F S H V P
Cat Felis silvestris
Mouse Mus musculus Q9D7G0 318 34830 S310 T H N G E S V S Y L F S H V P
Rat Rattus norvegicus P60892 318 34816 S310 T H N G E S V S Y L F S H V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZI49 325 35645 S317 T H N G E S V S Y L F S H V P
Frog Xenopus laevis Q7ZXC9 318 34683 S310 T H N G E S V S Y L F S H V P
Zebra Danio Brachydanio rerio NP_001070036 318 34782 S310 T H N G E S V S Y L F S H V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648345 350 38261 S342 T H N G E S V S Y L F S N V P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790052 315 34329 S307 T H N G E S V S Y L F S N V P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38063 327 35828 S319 L H N G E S V S Y L F T H A P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 97.1 92 N.A. 94 94.3 N.A. N.A. 88.3 91.1 93 N.A. 78 N.A. N.A. 85.2
Protein Similarity: 100 99 98.7 94.7 N.A. 97.1 97.1 N.A. N.A. 93.5 95.9 97.1 N.A. 84.5 N.A. N.A. 92.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 93.3 N.A. N.A. 93.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 100 N.A. N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 60.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 76.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 80 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % F
% Gly: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 100 0 0 0 0 0 0 0 0 0 0 84 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 100 0 0 0 0 0 0 0 0 0 17 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 100 0 100 0 0 0 92 0 0 0 % S
% Thr: 92 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % T
% Val: 0 0 0 0 0 0 100 0 0 0 0 0 0 92 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _