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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK11B
All Species:
14.55
Human Site:
S277
Identified Species:
26.67
UniProt:
P21127
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21127
NP_277021.1
795
92707
S277
M
E
E
R
D
L
L
S
D
L
Q
D
I
S
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096162
526
59263
S27
T
S
S
A
E
S
S
S
A
E
S
G
S
G
S
Dog
Lupus familis
XP_857026
795
92229
S277
M
E
E
R
D
L
L
S
D
L
Q
D
V
S
D
Cat
Felis silvestris
Mouse
Mus musculus
P24788
784
91495
L266
E
R
D
L
L
S
D
L
Q
D
I
S
D
S
E
Rat
Rattus norvegicus
P46892
436
49529
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026042
772
90216
E256
V
K
E
E
K
P
E
E
R
D
P
L
S
D
L
Frog
Xenopus laevis
NP_001086696
788
91927
S265
L
D
M
E
T
M
L
S
D
L
Q
D
V
S
D
Zebra Danio
Brachydanio rerio
NP_001008646
800
92940
S274
K
V
D
K
D
P
L
S
D
L
Q
D
I
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPC0
952
108820
S332
L
R
E
R
N
E
H
S
D
A
L
S
P
T
T
Honey Bee
Apis mellifera
XP_625138
840
98674
L316
K
E
V
S
R
L
E
L
E
A
R
R
M
K
R
Nematode Worm
Caenorhab. elegans
Q09437
719
83549
N181
S
S
T
T
S
P
D
N
D
K
S
P
H
K
K
Sea Urchin
Strong. purpuratus
XP_001192015
918
106921
E385
S
E
E
E
E
E
V
E
E
I
K
E
A
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
65.6
94.7
N.A.
95.2
50.1
N.A.
N.A.
89.8
84.7
77.3
N.A.
41.2
46.4
38.2
47
Protein Similarity:
100
N.A.
66
96.4
N.A.
97.2
52.7
N.A.
N.A.
92.9
91.5
86.2
N.A.
54.7
60.2
55.3
61.4
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
6.6
0
N.A.
N.A.
6.6
53.3
66.6
N.A.
26.6
13.3
6.6
20
P-Site Similarity:
100
N.A.
13.3
100
N.A.
20
0
N.A.
N.A.
20
80
80
N.A.
46.6
33.3
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
28.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
8
16
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
16
0
24
0
16
0
47
16
0
31
8
8
31
% D
% Glu:
8
31
39
24
16
16
16
16
16
8
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
8
0
16
0
0
% I
% Lys:
16
8
0
8
8
0
0
0
0
8
8
0
0
16
8
% K
% Leu:
16
0
0
8
8
24
31
16
0
31
8
8
0
0
8
% L
% Met:
16
0
8
0
0
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
24
0
0
0
0
8
8
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
31
0
0
0
0
% Q
% Arg:
0
16
0
24
8
0
0
0
8
0
8
8
0
0
8
% R
% Ser:
16
16
8
8
8
16
8
47
0
0
16
16
16
47
16
% S
% Thr:
8
0
8
8
8
0
0
0
0
0
0
0
0
8
8
% T
% Val:
8
8
8
0
0
0
8
0
0
0
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _