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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK11B
All Species:
11.82
Human Site:
S375
Identified Species:
21.67
UniProt:
P21127
Number Species:
12
Phosphosite Substitution
Charge Score:
0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21127
NP_277021.1
795
92707
S375
H
L
L
V
V
P
E
S
R
F
D
R
D
S
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096162
526
59263
G123
E
E
A
E
E
E
V
G
E
G
T
P
Q
S
S
Dog
Lupus familis
XP_857026
795
92229
S375
H
V
L
V
V
P
E
S
R
F
D
R
D
S
G
Cat
Felis silvestris
Mouse
Mus musculus
P24788
784
91495
S364
H
I
L
V
V
P
E
S
R
F
D
R
D
S
G
Rat
Rattus norvegicus
P46892
436
49529
V33
K
K
N
R
K
K
L
V
K
G
L
H
R
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026042
772
90216
S352
G
N
H
I
P
V
E
S
R
F
D
R
D
S
A
Frog
Xenopus laevis
NP_001086696
788
91927
D368
V
P
V
E
S
R
F
D
H
D
S
A
E
S
E
Zebra Danio
Brachydanio rerio
NP_001008646
800
92940
E380
D
S
E
V
S
A
E
E
E
E
E
E
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPC0
952
108820
D495
D
R
Q
D
V
G
A
D
A
S
P
S
S
S
T
Honey Bee
Apis mellifera
XP_625138
840
98674
N413
S
N
D
G
S
D
Y
N
N
P
S
P
L
S
V
Nematode Worm
Caenorhab. elegans
Q09437
719
83549
D293
D
A
L
H
S
D
D
D
A
D
S
D
E
D
K
Sea Urchin
Strong. purpuratus
XP_001192015
918
106921
D499
H
A
K
S
K
F
D
D
D
S
P
S
P
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
65.6
94.7
N.A.
95.2
50.1
N.A.
N.A.
89.8
84.7
77.3
N.A.
41.2
46.4
38.2
47
Protein Similarity:
100
N.A.
66
96.4
N.A.
97.2
52.7
N.A.
N.A.
92.9
91.5
86.2
N.A.
54.7
60.2
55.3
61.4
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
93.3
6.6
N.A.
N.A.
53.3
6.6
13.3
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
N.A.
6.6
100
N.A.
100
20
N.A.
N.A.
60
20
26.6
N.A.
13.3
13.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
28.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
0
0
8
8
0
16
0
0
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
0
8
8
0
16
16
31
8
16
31
8
31
8
0
% D
% Glu:
8
8
8
16
8
8
39
8
16
8
8
8
24
8
16
% E
% Phe:
0
0
0
0
0
8
8
0
0
31
0
0
0
0
0
% F
% Gly:
8
0
0
8
0
8
0
8
0
16
0
0
0
0
31
% G
% His:
31
0
8
8
0
0
0
0
8
0
0
8
0
0
0
% H
% Ile:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
8
8
8
0
16
8
0
0
8
0
0
0
0
0
8
% K
% Leu:
0
8
31
0
0
0
8
0
0
0
8
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
16
8
0
0
0
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
8
24
0
0
0
8
16
16
8
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
8
0
8
0
8
0
0
31
0
0
31
8
0
8
% R
% Ser:
8
8
0
8
31
0
0
31
0
16
24
16
8
62
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% T
% Val:
8
8
8
31
31
8
8
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _