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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK11B
All Species:
30.61
Human Site:
T705
Identified Species:
56.11
UniProt:
P21127
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21127
NP_277021.1
795
92707
T705
D
L
M
N
K
F
L
T
Y
F
P
G
R
R
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096162
526
59263
Y437
L
M
N
K
F
L
T
Y
F
P
G
R
R
I
S
Dog
Lupus familis
XP_857026
795
92229
T705
D
L
M
N
K
F
L
T
Y
F
P
G
R
R
V
Cat
Felis silvestris
Mouse
Mus musculus
P24788
784
91495
T694
D
L
M
N
K
F
L
T
Y
Y
P
G
R
R
I
Rat
Rattus norvegicus
P46892
436
49529
Y347
L
M
N
K
F
L
T
Y
Y
P
G
R
R
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026042
772
90216
T682
D
L
M
N
N
F
L
T
Y
Y
P
A
R
R
I
Frog
Xenopus laevis
NP_001086696
788
91927
T698
E
L
M
N
K
F
L
T
Y
C
P
A
K
R
I
Zebra Danio
Brachydanio rerio
NP_001008646
800
92940
T710
D
L
M
N
K
F
L
T
Y
C
P
A
K
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPC0
952
108820
L828
S
E
M
G
L
S
L
L
Q
G
L
L
T
Y
D
Honey Bee
Apis mellifera
XP_625138
840
98674
T746
E
L
L
N
K
F
L
T
Y
D
P
Q
Q
R
I
Nematode Worm
Caenorhab. elegans
Q09437
719
83549
L627
G
F
K
L
L
N
G
L
L
T
L
D
P
K
N
Sea Urchin
Strong. purpuratus
XP_001192015
918
106921
T829
E
L
L
N
R
F
L
T
Y
D
P
V
R
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
K209
F
A
E
M
C
N
R
K
P
I
F
S
G
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
65.6
94.7
N.A.
95.2
50.1
N.A.
N.A.
89.8
84.7
77.3
N.A.
41.2
46.4
38.2
47
Protein Similarity:
100
N.A.
66
96.4
N.A.
97.2
52.7
N.A.
N.A.
92.9
91.5
86.2
N.A.
54.7
60.2
55.3
61.4
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
93.3
13.3
N.A.
N.A.
80
73.3
80
N.A.
13.3
66.6
0
66.6
P-Site Similarity:
100
N.A.
20
100
N.A.
100
20
N.A.
N.A.
86.6
86.6
86.6
N.A.
13.3
86.6
6.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
28.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
24
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
16
0
0
0
0
0
% C
% Asp:
39
0
0
0
0
0
0
0
0
16
0
8
0
8
8
% D
% Glu:
24
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
0
16
62
0
0
8
16
8
0
0
0
0
% F
% Gly:
8
0
0
8
0
0
8
0
0
8
16
24
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
16
54
% I
% Lys:
0
0
8
16
47
0
0
8
0
0
0
0
16
8
0
% K
% Leu:
16
62
16
8
16
16
70
16
8
0
16
8
0
0
0
% L
% Met:
0
16
54
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
16
62
8
16
0
0
0
0
0
0
0
0
16
% N
% Pro:
0
0
0
0
0
0
0
0
8
16
62
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
8
8
0
0
% Q
% Arg:
0
0
0
0
8
0
8
0
0
0
0
16
54
62
0
% R
% Ser:
8
0
0
0
0
8
0
0
0
0
0
8
0
0
16
% S
% Thr:
0
0
0
0
0
0
16
62
0
8
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
16
70
16
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _