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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1B2
All Species:
36.67
Human Site:
S216
Identified Species:
53.78
UniProt:
P21281
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21281
NP_001684.2
511
56501
S216
Q
A
G
L
V
K
K
S
K
D
V
V
D
Y
S
Chimpanzee
Pan troglodytes
XP_001145161
513
56950
S210
Q
A
G
L
V
K
K
S
K
A
V
L
D
Y
H
Rhesus Macaque
Macaca mulatta
XP_001100869
540
59473
S245
Q
A
G
L
V
K
K
S
K
D
V
V
D
Y
S
Dog
Lupus familis
XP_543263
511
56560
S216
Q
A
G
L
V
K
K
S
K
D
V
V
D
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_598918
513
56772
S210
Q
A
G
L
V
K
K
S
K
A
V
L
D
Y
H
Rat
Rattus norvegicus
P62815
511
56532
S216
Q
A
G
L
V
K
K
S
K
D
V
V
D
Y
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49712
453
50207
A174
N
F
A
I
V
F
A
A
M
G
V
N
M
E
T
Frog
Xenopus laevis
NP_001080613
511
56429
S215
Q
A
G
L
V
K
K
S
K
D
V
M
D
Y
S
Zebra Danio
Brachydanio rerio
XP_002663572
509
56459
S215
Q
A
G
L
V
K
K
S
K
D
V
M
D
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P31409
490
54531
G196
A
G
L
V
K
L
P
G
K
S
V
L
D
D
H
Honey Bee
Apis mellifera
XP_624112
495
55126
G201
A
G
L
V
K
L
P
G
K
S
V
L
D
S
H
Nematode Worm
Caenorhab. elegans
Q19626
491
54732
Q196
V
R
Q
G
G
L
V
Q
L
P
D
R
P
H
E
Sea Urchin
Strong. purpuratus
XP_794151
487
54097
D193
A
G
L
V
K
L
P
D
K
G
V
L
D
G
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZN1
487
54286
S192
L
V
K
R
L
E
K
S
D
N
L
L
E
H
Q
Baker's Yeast
Sacchar. cerevisiae
P16140
517
57731
T197
Q
A
G
L
V
R
P
T
K
D
V
H
D
G
H
Red Bread Mold
Neurospora crassa
P11593
513
56790
N191
V
Q
R
Q
G
I
T
N
K
G
V
H
D
G
H
Conservation
Percent
Protein Identity:
100
84.4
94.4
98.8
N.A.
83.4
99
N.A.
N.A.
84.7
92.5
92.9
N.A.
86.5
85.7
82
84.5
Protein Similarity:
100
90.8
94.4
99.4
N.A.
90.2
99.4
N.A.
N.A.
86.6
95.8
96.4
N.A.
90
90
89.2
89.2
P-Site Identity:
100
80
100
100
N.A.
80
100
N.A.
N.A.
13.3
93.3
93.3
N.A.
20
20
0
20
P-Site Similarity:
100
86.6
100
100
N.A.
86.6
100
N.A.
N.A.
33.3
100
100
N.A.
33.3
33.3
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
73.7
75.6
74.4
Protein Similarity:
N.A.
N.A.
N.A.
83.3
82.4
82.2
P-Site Identity:
N.A.
N.A.
N.A.
13.3
60
20
P-Site Similarity:
N.A.
N.A.
N.A.
60
73.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
57
7
0
0
0
7
7
0
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
7
44
7
0
82
7
0
% D
% Glu:
0
0
0
0
0
7
0
0
0
0
0
0
7
7
7
% E
% Phe:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
19
57
7
13
0
0
13
0
19
0
0
0
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
13
0
13
44
% H
% Ile:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
7
0
19
50
57
0
82
0
0
0
0
0
0
% K
% Leu:
7
0
19
57
7
25
0
0
7
0
7
38
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
13
7
0
0
% M
% Asn:
7
0
0
0
0
0
0
7
0
7
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
25
0
0
7
0
0
7
0
0
% P
% Gln:
57
7
7
7
0
0
0
7
0
0
0
0
0
0
7
% Q
% Arg:
0
7
7
7
0
7
0
0
0
0
0
7
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
57
0
13
0
0
0
7
38
% S
% Thr:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
7
% T
% Val:
13
7
0
19
63
0
7
0
0
0
88
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _